Sing Hiem Yap

Medicine · Health Sciences

33h-index3.7kcitations141works0.02yr avg
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Research Topics

Liver Disease Diagnosis and Treatment(41), Hepatitis B Virus Studies(29), Hepatitis C virus research(25), Liver physiology and pathology(13), Drug Transport and Resistance Mechanisms(10)

Publications141 total

Hepatology 1986 Havekes et al. regulation LDLR in human hepatocytes
2014
Spinal muscular atrophy
International Journal of Obstetric Anesthesia·2003· 1 cited
TTV infection and its relation to serum transaminases in apparently healthy blood donors and in patients with clotting disorders who have been investigated previously for hepatitis C virus and GBV‐C/HGV infection in Belgium
Journal of Medical Virology·2002· 1 cited
An experimental evaluation of three preoperative radiation regimens for resectable rectal cancer
Annals of Surgical Oncology·2002· 6 cited
Aplastic anemia after transplantation for non-A, non-B, non-C fulminat hepatic failure: case report and review of the literature
Transplant International·2002· 11 cited
TTV infection and its relation to serum transaminases in apparently healthy blood donors and in patients with clotting disorders who have been investigated previously for hepatitis C virus and GBV‐C/HGV infection in Belgium
Journal of Medical Virology·2002· 13 cited
A novel strand-specific RT-PCR for detection of hepatitis C virus negative-strand RNA (replicative intermediate): evidence of absence or very low level of HCV replication in peripheral blood mononuclear cells
Journal of Virological Methods·2002· 50 cited
Hepatitis B virus infection in micro-carrier-attached immortalized human hepatocytes cultured in molecular-poreus membrane bags: a model for long-term episomal replication of HBV. (vol 5, pg 377, 1998)
2001· 1 cited
HVR1 quasispecies analysis from a long‐term culture of hepatitis C virus in Hep G2 derived cells grown in a haemodialysis cartridge
Journal of Viral Hepatitis·2001· 3 cited
Equally potent inhibitors of cholesterol synthesis in human hepatocytes have distinguishable effects on different cytochrome P450 enzymes
Biopharmaceutics & Drug Disposition·2000· 57 cited
Limitations of peritoneal lavage with antiseptics in prevention of recurrent colorectal cancer caused by tumor-cell seeding
Diseases of the Colon & Rectum·2000· 27 cited
Demonstration of the efficiency of a bioartificial liver in a potentially reversible large animal model of acute liver failure
Transplantation·2000
DEMONSTRATION OF THE EFFICIENCY OF A BIOARTIFICIAL LIVER IN A POTENTIALLY REVERSIBLE LARGE ANIMAL MODEL OF ACUTE LIVER FAILURE.
Transplantation·2000
Colorectal Cancer Cells in the Liver: from Micro- to Macrometastatic Disease
Acta chirurgica Belgica·2000· 2 cited
Demonstration of the efficiency of a bio-artificial liver in areversible large animal model of acute liver failure
Journal of Hepatology·2000
Involvement of phosphatidylserine and non-phospholipid components of the hepatitis B virus envelope in human Annexin V binding and in HBV infection in vitro
Journal of Hepatology·1999· 15 cited
Characterization of small hepatitis B surface antigen epitopes involved in binding to human annexin V
Journal of Viral Hepatitis·1999· 16 cited
Mycophenolic acid, an immunosuppressive agent, inhibits HBV replication <i>in vitro</i>
Journal of Viral Hepatitis·1999· 75 cited
A Phase I/Ii Study of Recombinant Human Interleukin–12 in Patients With Chronic Hepatitis C
Hepatology·1999· 56 citedOpen Access
Transfection of the HCV core gene induces malignant transformation in non-tumorigenic human hepatocytes: an in vitro model for the study of HCV associated hepatocarcinogenesis
1999
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Frequent Co-authors

Han Moshage(16), David A. Shafritz(7), P. Hans(7), Roger Strair(5), H.M.J. Roelofs(4), P. J. M. Rijntjes(4), J C Hafkenscheid(3), Jos van Pelt(3), P.J.L. van Gemert(3), Johan Fevery(3), G.P.B.M. Mol-Backx(3), Gerard C.M. Selten(3), Bouke P. C. Hazenberg(2), LA Aarden(2), Gerald Thiel(2), W. Nieuwenhuizen(2), Mark Α. Zern(2), Odette Pos(2), T. J. M. van Ditzhuijsen(2), Stefaan Keppens(2)