Christos Roussakis

Cibles et Médicaments des Infections et de l'Immunité

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index2.9kcitations114works0.02yr avg
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Research Topics

Marine Sponges and Natural Products(50), Microbial Natural Products and Biosynthesis(18), Synthetic Organic Chemistry Methods(17), Synthesis and Biological Activity(17), Seaweed-derived Bioactive Compounds(10)

Publications111 total

Targeting Degradation of EGFR through the Allosteric Site Leads to Cancer Cell Detachment-Promoted Death
Cancers·2019· 16 citedOpen Access
Steroids from Marine-Derived Fungi: Evaluation of Antiproliferative and Antimicrobial Activities of Eburicol
Marine Drugs·2019· 25 citedOpen Access
Isolation and structure elucidation of secondary metabolites of two Greek endemic Inula species. Biological activities
Phytochemistry Letters·2019· 8 cited
Silicon Coordinates DNA Replication with Transcription of the Replisome Factors in Diatom Algae
Plant Molecular Biology Reporter·2018· 2 cited
Haspin: a promising target for the design of inhibitors as potent anticancer drugs
Drug Discovery Today·2017· 54 cited
Chemical constituents from Cordia alliodora and C. colloccoca (Boraginaceae) and their biological activities
Fitoterapia·2016· 23 cited
Discovery of Novel (Imidazo[1,2-a]pyrazin-6-yl)ureas as Antiproliferative Agents Targeting P53 in Non-small Cell Lung Cancer Cell Lines.
PubMed·2016· 3 cited
Lipid Composition, Fatty Acids and Sterols in the Seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): An Analysis from Nutritional, Chemotaxonomic, and Antiproliferative Activity Perspectives
Marine Drugs·2015· 191 citedOpen Access
Research on the immunosuppressive activity of ingredients contained in sunscreens
Archives of Dermatological Research·2015· 20 cited
Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells
Scientific Reports·2014· 23 citedOpen Access
Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines
European Journal of Medicinal Chemistry·2013· 42 cited
Comparison of photoprotection efficiency and antiproliferative activity of ZnO commercial sunscreens and CeO2
Materials Letters·2013· 31 cited
Antimalarial Activity of Axidjiferosides, New β-Galactosylceramides from the African Sponge Axinyssa djiferi
Marine Drugs·2013· 27 citedOpen Access
ChemInform Abstract: Antiproliferative Activity Against Human Non‐Small Lung Cancer of Two O‐Alkyl‐diglycosylglycerols from the Marine Sponges Myrmekioderma dendyi and Trikentrion laeve.
ChemInform·2012
Antiproliferative activity against human non-small cell lung cancer of two O-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeve
European Journal of Medicinal Chemistry·2012· 22 cited
Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines
European Journal of Medicinal Chemistry·2010· 59 cited
Synthesis of the cyclic heptapeptide axinellin A
Tetrahedron·2009· 36 cited
Cytotoxic bromoditerpenes from the red alga Sphaerococcus coronopifolius
Tetrahedron·2008· 33 cited
CCDC 671358: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
CCDC 671458: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
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Frequent Co-authors

Cécile Debitus(13), Luigi Minale(8), J.F. Verbist(6), Angela Zampella(6), Maria Valeria D’Auria(6), İoanna Chinou(5), Luigi Gomez Paloma(5), Jean‐François Verbist(5), D Riou(4), Maria Iorizzi(4), Franco Zollo(4), Dimitri Moreau(4), Gaëtane Wielgosz‐Collin(3), J F Biard(3), Valérie Le Bert(3), Christophe Tomasoni(3), Catherine Harvala(3), Philippe Amade(3), Simona De Marino(3), Yves François Pouchus(3)