Jozef Goris

KU Leuven — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index9.0kcitations214works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(55), Protein Tyrosine Phosphatases(47), PI3K/AKT/mTOR signaling in cancer(17), Biochemical and Molecular Research(17), Mitochondrial Function and Pathology(16)

Publications214 total

PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration
Journal of Cell Science·2016· 28 citedOpen Access
Molecular Implication of PP2A and Pin1 in the Alzheimer's Disease Specific Hyperphosphorylation of Tau
PLoS ONE·2011· 66 citedOpen Access
Mice lacking phosphatase PP2A subunit PR61/B’δ ( <i>Ppp2r5d</i> ) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β
Proceedings of the National Academy of Sciences·2011· 114 citedOpen Access
Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells
Nature Cell Biology·2010· 335 citedOpen Access
D-PTPA is an essential activator of Phosphatase 2A in multiple developmental signaling pathways in Drosophila melanogaster
2010
Generation and preliminary characterization of PTPA gene-trapped mice
2010
Characterization of the tumor phenotype of Protein Phosphatase 2A PR61/B'delta knockout mice
2010
PP2AT61ɛ Is an Inhibitor of MAP4K3 in Nutrient Signaling to mTOR
Molecular Cell·2010· 123 citedOpen Access
An automated workflow for high throughput MLVA using the BioNumerics® software, able to deal with varying experimental settings
International Journal of Infectious Diseases·2010Open Access
Genetic inactivation of a specific PP2A subunit, PR61/B'delta, in a mouse model generates tauopathy through an indirect mechanism
2010
Protein phosphatase 2A PR130/B”α:1 subunit binds to the SH2 domain‐containing inositol polyphosphate 5‐phosphatase 2 and prevents epidermal growth factor (EGF)‐induced EGF receptor degradation sustaining EGF‐mediated signaling
The FASEB Journal·2009· 46 cited
PIV-9 High throughput viral typing of influenza H1N1 using the automatic alignment &amp; mutation analysis tool in the bionumerics software
Journal of Clinical Virology·2009
Mitotic exit control by PP2ACA/R1A/R2A in human cells
2009
Tau hyperphosphorylation and sensorimotor impairment in mice lacking the PP2A regulatory subunit PR61/B’delta
2009
A novel biological function of the PP2A PR130/B"alpha1 complex in cell migration and adhesion
2009
On the mechanism of the PP2A phosphatase activator (PTPA) and its interplay with PME-1
2009
Specific regulation of protein phosphatase 2A PR72/B′′ subunits by calpain
Biochemical and Biophysical Research Communications·2009· 13 cited
Regulation of Epidermal Growth Factor-induced EGF receptor degradation by SH2 domain-containing Inositol Polyphosphate 5-Phosphatase 2 (SHIP2) and a specific Protein Phosphatase 2A (PP2A) complex
2009
Protein phosphatase 2AT130 is an endogenous phosphatase for Polycystin-2
2009
The Protein Phosphatase 2A ‘code’: how post-translational modifications of the PP2A catalytic subunit determine regulatory subunit selection
2009
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Frequent Co-authors

Wilfried Merlevede(19), Veerle Janssens(17), Christine Van Hoof(10), Etienne Waelkens(8), Sari Longin(6), Brian A. Hemmings(6), Jackie R. Vandenheede(6), Erik Martens(6), Patrizia Agostinis(6), Justin Vijay Louis(5), Ilse Stevens(5), Rita Derua(4), Jan Jordens(4), Lorenzo A. Pinna(4), Eva‐Maria Mandelkow(3), Peter Cron(3), Karen Zwaenepoel(3), Chris Van Hoof(3), Gerard Drewes(2), Peter Hendrix(2)