Cécile Orsini

Sanofi (France) — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.1kcitations31works0.02yr avg
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Research Topics

Virus-based gene therapy research(13), CRISPR and Genetic Engineering(9), Viral Infectious Diseases and Gene Expression in Insects(9), RNA Interference and Gene Delivery(5), Pancreatic function and diabetes(3)

Publications31 total

Abstract 3269: Ablation of Cbl-b gene function leads to increased activation and resistance to immunosuppression in human primary T lymphocytes
Cancer Research·2020
Abstract 242: Identification of biomarkers predicting sensitivity to GLS1 inhibition using a CRISPR screen
Cancer Research·2020
A 3D Human Liver Model of Nonalcoholic Steatohepatitis
Journal of Clinical and Translational Hepatology·2020· 21 citedOpen Access
ABHD11, a new diacylglycerol lipase involved in weight gain regulation
PLoS ONE·2020· 14 citedOpen Access
A 3D human liver model of nonalcoholic steatohepatitis
2020· 10 citedOpen Access
A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology
Stem Cell Reports·2019· 70 citedOpen Access
Abstract 1272: Whole genome Crispr screening to identify potential SERD molecule resistance mechanisms
Experimental and Molecular Therapeutics·2019
Abstract 1272: Whole genome Crispr screening to identify potential SERD molecule resistance mechanisms
Cancer Research·2019
Type 2/Th2‐driven inflammation impairs olfactory sensory neurogenesis in mouse chronic rhinosinusitis model
Allergy·2018· 65 citedOpen Access
Integrated approaches for Fabry disease biomarker discovery and qualification
Molecular Genetics and Metabolism·2018
Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2016· 19 citedOpen Access
Effective clearance of GL‐3 in a human iPSC‐derived cardiomyocyte model of Fabry disease
Journal of Inherited Metabolic Disease·2014· 51 cited
Generation of a Drug-inducible Reporter System to Study Cell Reprogramming in Human Cells
Journal of Biological Chemistry·2012· 18 citedOpen Access
Comparison of promoter region constructs for<i>in vivo</i>intramuscular expression
The Journal of Gene Medicine·2006· 13 cited
Positive <i>in vivo</i> heterologous gene regulation by electric pulses delivery with metallothionein I gene promoter
The Journal of Gene Medicine·2005· 4 cited
Heterogeneous Nuclear Ribonucleoprotein A1 Is a Novel Internal Ribosome Entry Site trans-Acting Factor That Modulates Alternative Initiation of Translation of the Fibroblast Growth Factor 2 mRNA
Journal of Biological Chemistry·2004· 152 citedOpen Access
Transcriptional activation of the metallothionein I gene by electric pulses <i>in vivo</i>: basis for the development of a new gene switch system
The Journal of Gene Medicine·2003· 12 cited
Viral and non-viral gene therapy partially prevents experimental cisplatin-induced neuropathy
Gene Therapy·2002· 34 cited
Continuous Delivery of Neurotrophin 3 by Gene Therapy Has a Neuroprotective Effect in Experimental Models of Diabetic and Acrylamide Neuropathies
Human Gene Therapy·2001· 79 cited
MUSEAP , a novel reporter gene for the study of long-term gene expression in immunocompetent mice
Gene·2001· 46 cited
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Frequent Co-authors

Michel Perricaudet(10), Emmanuelle Vigne(9), P Yeh(7), Vincent Mikol(7), J F Dedieu(6), Michel Didier(6), Patrice Denèfle(5), Jean‐Claude Guillemot(5), P. Delaère(4), Marie‐Dominique Bock(4), Sandrine Roche(4), Daniel Scherman(4), Laurent Debüssche(4), Christophe Lanneau(4), Patrice Yeh(3), Philippe Kennel(3), Françoise Finiels(3), Frédéric Revah(3), Jacques Mallet(3), John P. Leonard(3)