Peg Davis

University of Arizona — United States

Neuroscience · Life Sciences

38h-index4.2kcitations166works0.02yr avg
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Research Topics

Neuropeptides and Animal Physiology(144), Receptor Mechanisms and Signaling(85), Chemical Synthesis and Analysis(73), Pharmacological Receptor Mechanisms and Effects(56), Pain Mechanisms and Treatments(14)

Publications166 total

Structure–Activity Relationships of [des-Arg<sup>7</sup>]Dynorphin A Analogues at the κ Opioid Receptor
Journal of Medicinal Chemistry·2016· 14 citedOpen Access
Design synthesis and structure–activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands
Bioorganic & Medicinal Chemistry·2015· 2 citedOpen Access
Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations
Bioorganic & Medicinal Chemistry Letters·2015· 4 citedOpen Access
Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain
Journal of Medicinal Chemistry·2015· 20 citedOpen Access
Design, synthesis and biological evaluation of multifunctional ligands targeting opioid and bradykinin 2 receptors
Bioorganic & Medicinal Chemistry Letters·2015· 5 citedOpen Access
Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands
Bioorganic & Medicinal Chemistry·2015· 4 citedOpen Access
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives
Bioorganic & Medicinal Chemistry Letters·2015· 13 citedOpen Access
Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities
Bioorganic & Medicinal Chemistry Letters·2015· 14 citedOpen Access
Effects of Methyl and Halogens in Analgesic Peptide Molecules for Their Potent Agonist Activities at MOR/DOR and Antagonist Activity at NK1R
2015Open Access
Novel Cyclic Biphalin Analogue with Improved Antinociceptive Properties
ACS Medicinal Chemistry Letters·2014· 34 citedOpen Access
Building a Better Analgesic: Multifunctional Compounds that Address Injury-Induced Pathology to Enhance Analgesic Efficacy while Eliminating Unwanted Side Effects
Journal of Pharmacology and Experimental Therapeutics·2013· 31 citedOpen Access
Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities
Bioorganic & Medicinal Chemistry Letters·2013· 13 citedOpen Access
Chiral Effect of a Phe Residue in Position 3 of the Dmt<sup>1</sup>-<scp>l</scp>(or <scp>d</scp>)-Tic<sup>2</sup> Analogues on Opioid Functional Activities
ACS Medicinal Chemistry Letters·2013· 3 citedOpen Access
Effect of anchoring 4-anilidopiperidines to opioid peptides
Bioorganic & Medicinal Chemistry Letters·2013· 8 citedOpen Access
Biological Active Analogues of the Opioid Peptide Biphalin: Mixed α/β<sup>3</sup>-Peptides
Journal of Medicinal Chemistry·2013· 34 citedOpen Access
TY032, a potent opioid agonist/neurokinin 1 antagonist produces analgesia without motor impairment or sedation
The FASEB Journal·2013
Design, Synthesis and Biological Evaluation of Multivalent Ligands with μ/δ Opioid Agonist (μ-preferring) /NK-1 Antagonist Activities
2013· 1 citedOpen Access
<i>cis</i>-4-Amino-<scp>l</scp>-proline Residue As a Scaffold for the Synthesis of Cyclic and Linear Endomorphin-2 Analogues: Part 2
Journal of Medicinal Chemistry·2012· 23 cited
The <i>cis</i>-4-Amino-<scp>l</scp>-proline Residue as a Scaffold for the Synthesis of Cyclic and Linear Endomorphin-2 Analogues
Journal of Medicinal Chemistry·2012· 34 citedOpen Access
Afferent drive elicits ongoing pain in a model of advanced osteoarthritis
Pain·2012· 132 citedOpen Access
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Frequent Co-authors

Frank Porreca(41), Victor J. Hruby(35), Henry I. Yamamura(18), Josephine Lai(17), Shou-wu Ma(14), Edward J. Bilsky(13), Richard B. Rothman(8), Todd W. Vanderah(8), Adriano Mollica(8), Robin Polt(6), Kenner C. Rice(6), Takashi Yamamoto(6), Padma Nair(6), Francesco Pinnen(6), Edita Navratilova(5), Richard D. Egleton(4), Heng Xu(4), Róbert Horváth(4), Christina M. Dersch(4), Aleksandra Misicka(4)