R.D. Pinnock

Biogen (United Kingdom) — United Kingdom

Neuroscience · Life Sciences

33h-index3.4kcitations60works1.02yr avg
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Research Topics

Neuropeptides and Animal Physiology(21), Receptor Mechanisms and Signaling(21), Neuroscience and Neuropharmacology Research(15), Ion channel regulation and function(13), Pain Mechanisms and Treatments(10)

Publications60 total

Identification and characterization of human <i>KALRN</i> mRNA and Kalirin protein isoforms
Cerebral Cortex·2024· 1 citedOpen Access
Supplementary Material for: Comparison of Wavelet Transform and Time-Domain Analysis of Second Trimester Uterine Artery Doppler Waveforms in Screening for Pre-Eclampsia
Figshare·2013Open Access
Lack-of-drug danger
The New Scientist·2007
Drug discovery
The New Scientist·2007
Cellular and molecular action of the putative GABA-mimetic, gabapentin
Cellular and Molecular Life Sciences·2003· 148 citedOpen Access
Hydrogen‐Peroxide‐Induced Toxicity of Rat Striatal Neurones Involves Activation of a Non‐Selective Cation Channel
The Journal of Physiology·2003· 75 citedOpen Access
Identification of MEK1 as a novel target for the treatment of neuropathic pain
British Journal of Pharmacology·2003· 110 citedOpen Access
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression
Neuropharmacology·2002· 148 cited
Gabapentin inhibits high‐threshold calcium channel currents in cultured rat dorsal root ganglion neurones
British Journal of Pharmacology·2002· 240 citedOpen Access
Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons
Neuroscience Letters·2001· 66 cited
Developmental expression of the novel voltage‐gated sodium channel auxiliary subunit β3, in rat CNS
The Journal of Physiology·2001· 88 citedOpen Access
β3, a novel auxiliary subunit for the voltage gated sodium channel is upregulated in sensory neurones following streptozocin induced diabetic neuropathy in rat
Neuroscience Letters·2001· 51 cited
β3, a novel auxiliary subunit for the voltage‐gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain
European Journal of Neuroscience·2000· 97 cited
Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes
Neuroscience·1999· 34 cited
Bombesin‐like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors
The Journal of Physiology·1999· 44 citedOpen Access
Serotonin depolarizes hippocampal interneurones in the rat stratum oriens by interaction with 5HT2 receptors
Neuroscience Letters·1999· 17 cited
Corticotropin-Releasing Factor Type 1 and Type 2α Receptors Regulate Phosphorylation of Calcium/Cyclic Adenosine 3′,5′-Monophosphate Response Element-Binding Protein and Activation of p42/p44 Mitogen-Activated Protein Kinase
Endocrinology·1999· 87 citedOpen Access
Glucose‐receptive neurones in the rat ventromedial hypothalamus express K<sub>ATP</sub> channels composed of Kir6.1 and SUR1 subunits
The Journal of Physiology·1999· 90 citedOpen Access
Hydrogen Peroxide Induces Intracellular Calcium Overload by Activation of a Non-selective Cation Channel in an Insulin-secreting Cell Line
Journal of Biological Chemistry·1999· 109 citedOpen Access
PD 176252 — The first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist
Bioorganic & Medicinal Chemistry Letters·1998· 50 citedOpen Access
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Frequent Co-authors

G.N. Woodruff(10), A. K. Dixon(8), David B. Sattelle(7), K. Lee(5), Nirmala Suman‐Chauhan(5), Joel W. Hughes(4), P. Boden(4), K Lee(4), Matthew D. Hall(4), Kevin Lee(4), David C. Horwell(3), Bhaval S. Shah(3), Edward B. Stevens(3), Peter J. Richardson(3), Martyn C. Pritchard(3), Kathy Sutton(2), Duncan J. Martin(2), Roderick H. Scott(2), C. Peter Downes(2), Michel Goedert(2)