Joseph D. Armstrong

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.4kcitations64works4.02yr avg
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Research Topics

Chemical Synthesis and Analysis(20), Asymmetric Synthesis and Catalysis(16), Asymmetric Hydrogenation and Catalysis(13), Chemical Synthesis and Reactions(7), Synthesis and Biological Evaluation(7)

Publications64 total

Development of a Safer Continuous Flow Process for B<sub>2</sub>(OH)<sub>4</sub>-Mediated Chemoselective Reduction of Nitroarenes to Anilines
Organic Process Research & Development·2024· 1 cited
Synthesis of Chiral 1,2-Amino Alcohol-Containing Compounds Utilizing Ruthenium-Catalyzed Asymmetric Transfer Hydrogenation of Unprotected α-Ketoamines
The Journal of Organic Chemistry·2024· 7 cited
Design and Discovery of Water-Soluble Benzooxaphosphole-Based Ligands for Hindered Suzuki–Miyaura Coupling Reactions with Low Catalyst Load
Organic Letters·2023· 5 cited
Facile and Scalable Methodology for the Pyrrolo[2,1- <i>f</i> ][1,2,4]triazine of Remdesivir
Organic Process Research & Development·2022· 12 citedOpen Access
Progress Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
ACS Omega·2021· 51 citedOpen Access
Progress Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
DSpace@MIT (Massachusetts Institute of Technology)·2021Open Access
Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir
2021Open Access
Facile and Scalable Methodology for the Pyrrolo[2,1-f][1,2,4]triazine of Remdesivir
2021· 1 citedOpen Access
Progress Towards a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
2021Open Access
Progress Towards a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
2021· 1 citedOpen Access
Correction to “Highly Efficient Asymmetric Synthesis of Sitagliptin”
Journal of the American Chemical Society·2020· 1 cited
Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions
Bioconjugate Chemistry·2018· 6 cited
Sitagliptin (Januvia): A Treatment for Type 2 Diabetes
2010· 1 cited
Synthesis of Sitagliptin, the Active Ingredient in Januvia® and Janumet®
2010· 12 cited
Highly Efficient Asymmetric Synthesis of Sitagliptin
Journal of the American Chemical Society·2009· 304 cited
Definitive CAD/CAM‐Guided Prosthesis for Immediate Loading of Bone‐Grafted Maxilla: A Case Report
Clinical Implant Dentistry and Related Research·2006· 54 citedOpen Access
Highly Diastereoselective Catalytic Meerwein—Ponndorf—Verley Reductions.
ChemInform·2006Open Access
Highly Diastereoselective Catalytic Meerwein−Ponndorf−Verley Reductions
The Journal of Organic Chemistry·2005· 54 cited
Proline-Catalyzed, Asymmetric Mannich Reactions in the Synthesis of a DPP-IV Inhibitor
The Journal of Organic Chemistry·2005· 81 cited
Detection and Elimination of Product Inhibition from the Asymmetric Catalytic Hydrogenation of Enamines
Organic Letters·2005· 47 cited
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Frequent Co-authors

R. P. Volante(13), Yi Hsiao(7), Norihiro Ikemoto(7), Chris H. Senanayake(7), Karl B. Hansen(6), Feng Xu(6), Jaume Balsells(6), Edward J. J. Grabowski(6), Nan Zheng(6), Fred J. Fleitz(6), Li Li(6), Jennifer Keller(6), Nelo R. Rivera(5), Michele Kubryk(5), J. Christopher McWilliams(5), Ronald H. Szumigala(5), Gopal Sirasani(5), Thorsten Rosner(4), Bryon Simmons(4), Yongkui Sun(4)