Robert M. Grainger

University of Virginia — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index4.5kcitations68works0.02yr avg
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Research Topics

Animal Genetics and Reproduction(17), Developmental Biology and Gene Regulation(10), CRISPR and Genetic Engineering(7), Physiological and biochemical adaptations(6), Amphibian and Reptile Biology(5)

Publications68 total

Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond
The Ocular Surface·2023· 8 cited
Production of Transgenic F<sub>0</sub>Animals and Permanent Lines by Sperm Nuclear Transplantation in<i>Xenopus tropicalis</i>
Cold Spring Harbor Protocols·2022· 2 cited
Best Practices for<i>Xenopus tropicalis</i>Husbandry
Cold Spring Harbor Protocols·2022· 3 citedOpen Access
Preparation of Intact Nuclei for Single-Nucleus Omics Using Frozen Cell Suspensions from Mutant Embryos of<i>Xenopus tropicalis</i>
Cold Spring Harbor Protocols·2022· 3 cited
Homology-Directed Repair by CRISPR–Cas9 Mutagenesis in<i>Xenopus</i>Using Long Single-Stranded Donor DNA Templates via Simple Microinjection of Embryos
Cold Spring Harbor Protocols·2022· 4 citedOpen Access
Gynogenetic Production of Embryos in<i>Xenopus tropicalis</i>Using a Cold Shock Procedure: Rapid Screening Method for Gene Editing Phenotypes
Cold Spring Harbor Protocols·2022· 4 cited
Modeling Human Genetic Disorders with CRISPR Technologies in <i>Xenopus</i>
Cold Spring Harbor Protocols·2021· 6 cited
Anterior chamber angle in aniridia with and without glaucoma
SHILAP Revista de lepidopterología·2019· 2 citedOpen Access
&lt;p&gt;Anterior chamber angle in aniridia with and without glaucoma&lt;/p&gt;
Clinical ophthalmology·2019· 22 citedOpen Access
no privacy, a Xenopus tropicalis mutant, is a model of human Hermansky-Pudlak Syndrome and allows visualization of internal organogenesis during tadpole development
Developmental Biology·2016· 32 cited
Functional Cloning Using a &lt;em&gt;Xenopus&lt;/em&gt; Oocyte Expression System
Journal of Visualized Experiments·2016
Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
Developmental Biology·2015· 73 cited
Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character
Developmental Biology·2014· 33 citedOpen Access
Cas9-Based Genome Editing in Xenopus tropicalis
Methods in enzymology on CD-ROM/Methods in enzymology·2014· 106 cited
Disruption of Autoregulatory Feedback by a Mutation in a Remote, Ultraconserved PAX6 Enhancer Causes Aniridia
The American Journal of Human Genetics·2013· 200 citedOpen Access
Simple and efficient CRISPR/Cas9‐mediated targeted mutagenesis in <i>Xenopus tropicalis</i>
genesis·2013· 283 citedOpen Access
Development of xenopus resource centers: The national xenopus resource and the european xenopus resource center
genesis·2012· 61 citedOpen Access
Comparative Genomics-Based Identification and Analysis of Cis-Regulatory Elements
Methods in molecular biology·2012· 9 citedOpen Access
Xenopus tropicalis as a Model Organism for Genetics and Genomics: Past, Present, and Future
Methods in molecular biology·2012· 50 citedOpen Access
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development
Developmental Biology·2011· 13 citedOpen Access
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Frequent Co-authors

Richard M. Harland(17), Hazel Sive(15), Takuya Nakayama(9), Margaret B. Fish(6), Marilyn Fisher(5), Amanda Cox(4), Peter A. Netland(3), Ira L. Blitz(2), Enrique Amaya(2), Hajime Ogino(2), Lyle B. Zimmerman(2), Timothy C. Grammer(2), Akinleye O. Odeleye(2), Jane E. Mannion(2), T. Les Cook(2), Carol A. Zygar(2), Keisuke Nakajima(2), Yoshio Yaoita(2), James D. Lauderdale(2), Matthew Guille(2)