Yvonne Ng

Singapore National Eye Center — Singapore

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index965citations21works3.02yr avg
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Research Topics

Metabolism, Diabetes, and Cancer(8), PI3K/AKT/mTOR signaling in cancer(6), Protein Kinase Regulation and GTPase Signaling(3), Adipokines, Inflammation, and Metabolic Diseases(3), Cellular transport and secretion(3)

Publications21 total

Toward automated assessment of conjunctival hyperemia: A semisupervised artificial intelligence approach
Annals of the New York Academy of Sciences·2025· 3 citedOpen Access
HOXC10 Suppresses Browning to Maintain White Adipocyte Identity
Diabetes·2021· 11 citedOpen Access
ASLAN003, a potent dihydroorotate dehydrogenase inhibitor for differentiation of acute myeloid leukemia
Haematologica·2019· 78 citedOpen Access
HOXC10 suppresses browning of white adipose tissues
Experimental & Molecular Medicine·2017· 30 citedOpen Access
Selective Insulin Resistance in Adipocytes
Journal of Biological Chemistry·2015· 108 citedOpen Access
A Study of Urban Heat Island using “Local Climate Zones” – The Case of Singapore
British Journal of Environment and Climate Change·2015· 46 cited
Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with CCO10
2014
Novel Systems for Dynamically Assessing Insulin Action in Live Cells Reveals Heterogeneity in the Insulin Response
Traffic·2012· 30 citedOpen Access
The Rab GTPase-Activating Protein TBC1D4/AS160 Contains an Atypical Phosphotyrosine-Binding Domain That Interacts with Plasma Membrane Phospholipids To Facilitate GLUT4 Trafficking in Adipocytes
Molecular and Cellular Biology·2012· 65 citedOpen Access
Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes
Journal of Biological Chemistry·2011· 75 citedOpen Access
Insulin Signaling Paradox Characterizes Human Insulin Resistance
2011
Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes
Biochemical Journal·2011· 52 cited
Akt inhibitors reduce glucose uptake independently of their effects on Akt
Biochemical Journal·2010· 26 cited
Dissecting the Mechanism of Insulin Resistance Using a Novel Heterodimerization Strategy to Activate Akt
Journal of Biological Chemistry·2009· 19 citedOpen Access
Cluster Analysis of Insulin Action in Adipocytes Reveals a Key Role for Akt at the Plasma Membrane
Journal of Biological Chemistry·2009· 52 citedOpen Access
Identification of a Distal GLUT4 Trafficking Event Controlled by Actin Polymerization
Molecular Biology of the Cell·2009· 86 citedOpen Access
Membrane boundary extraction using circular multiple paths
Pattern Recognition·2008· 14 cited
Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes
Cell Metabolism·2008· 194 citedOpen Access
Membrane Boundary Extraction Using a Circular Shortest Path Technique
AIP conference proceedings·2007· 2 cited
Expression of the Human Myotonic Dystrophy Kinase-related Cdc42-binding Kinase γ Is Regulated by Promoter DNA Methylation and Sp1 Binding
Journal of Biological Chemistry·2004· 28 citedOpen Access
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Frequent Co-authors

David E. James(13), Shi‐Xiong Tan(8), Georg Ramm(4), Jamie Lopez Bernal(4), Jacqueline Stöckli(4), James G. Burchfield(4), Daniel J. Fazakerley(3), Adelle C.F. Coster(3), Pascal Vallotton(3), Weiping Han(3), Christopher C. Meoli(2), Katarina Mele(2), William E. Hughes(2), Thomas Leung(2), Ivan Tan(2), Louis Lim(2), Changming Sun(2), Dadong Wang(2), Kelsey H. Fisher‐Wellman(1), Himani Pant(1)