Alex Disney

Medicine · Health Sciences

24h-index2.9kcitations66works0.02yr avg
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Research Topics

Dialysis and Renal Disease Management(18), Renal Transplantation Outcomes and Treatments(10), Neuropeptides and Animal Physiology(10), Renal and Vascular Pathologies(7), Pharmacological Receptor Mechanisms and Effects(7)

Publications65 total

Opioid Antagonists from the Orvinol Series as Potential Reversal Agents for Opioid Overdose
ACS Chemical Neuroscience·2022· 11 citedOpen Access
Long‐term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox
Pharmacology Research & Perspectives·2021· 17 citedOpen Access
Countermeasures for Preventing and Treating Opioid Overdose
Clinical Pharmacology & Therapeutics·2020· 66 citedOpen Access
Methocinnamox (MCAM) antagonizes the behavioral suppressant effects of morphine without impairing delayed matching-to-sample accuracy in rhesus monkeys
Psychopharmacology·2020· 10 citedOpen Access
Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys
Neuropsychopharmacology·2020· 22 citedOpen Access
Effects of Acute and Repeated Methocinnamox Treatment on Fentanyl Self‐administration in Rhesus Monkeys
The FASEB Journal·2020· 1 cited
Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats
Journal of Pharmacology and Experimental Therapeutics·2019· 24 citedOpen Access
Methocinnamox (MCAM) is an Effective Long‐Term Antagonist of Peripheral Mu, but not Kappa or Delta Opioid Receptors <i>In Vivo</i>
The FASEB Journal·2019· 2 cited
Methocinnamox (MCAM) is a Selective, Long Acting Antagonist at Mu Opioid Receptors In Vitro
The FASEB Journal·2019· 2 cited
Methocinnamox: Sustained Antagonism of the Antinociceptive Effects of Morphine and Not Spiradoline in Rats
The FASEB Journal·2019· 3 cited
Reversal and Prevention of the Respiratory-Depressant Effects of Heroin by the Novel μ-Opioid Receptor Antagonist Methocinnamox in Rhesus Monkeys
Journal of Pharmacology and Experimental Therapeutics·2018· 28 citedOpen Access
Long-Lasting Effects of Methocinnamox on Opioid Self-Administration in Rhesus Monkeys
Journal of Pharmacology and Experimental Therapeutics·2018· 33 citedOpen Access
798. The Role of Whole-Genome Sequencing in Characterizing the Mechanism of Action of Anti-Tuberculosis Compounds: Demonstrated With Para-Amino Salicylic Acid and Its Analogue
Open Forum Infectious Diseases·2018Open Access
The novel μ‐opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception
British Journal of Pharmacology·2018· 169 citedOpen Access
The novel, pseudo-irreversible mu opioid receptor antagonist SH-1 attenuates the reinforcing and respiratory-depressant effects of heroin in rhesus monkeys
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
Recurrence of IgA Deposits/Disease in Grafts
Contributions to nephrology·2015· 20 cited
is mediated by GABAergic inhibition Cholinergic suppression of visual responses in primate V1
2012
Psychosocial variables are associated with being wait-listed, but not with receiving a kidney transplant in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
Nephrology Dialysis Transplantation·2011· 31 citedOpen Access
Atrial fibrillation in hemodialysis patients: clinical features and associations with anticoagulant therapy
Kidney International·2010· 400 cited
The Burden of Amputation Among Hemodialysis Patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS)
American Journal of Kidney Diseases·2009· 86 cited
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Frequent Co-authors

Stephen M. Husbands(12), Charles P. France(7), Lisa R. Gerak(6), Peter G. Kerr(4), Margaret McCredie(4), David C.H. Harris(4), Timothy H. Mathew(4), David R. Maguire(4), John H. Stewart(3), Ronald L. Pisoni(3), N P Hurst(3), John Agar(3), James H. Woods(3), P Coates(3), Vlado Perkovic(3), Elaine M. Jennings(3), Kelly A. Berg(3), William P. Clarke(3), Bruce Robinson(2), Patrick Maisonneuve(2)