Alejandro Martínez

Medicine · Health Sciences

9h-index665citations22works0.02yr avg
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Research Topics

Lung Cancer Treatments and Mutations(7), Cancer Genomics and Diagnostics(7), Colorectal Cancer Treatments and Studies(5), Virus-based gene therapy research(3), PI3K/AKT/mTOR signaling in cancer(3)

Publications22 total

Cancer risk in patients with rheumatoid arthritis receiving biologic and targeted synthetic disease-modifying antirheumatic drugs: results from the BIOBADASER III registry
Lara D. Veeken·2025
Multicenter Real-World Data of Subsequent Chemotherapy after Progression to PARP Inhibitors in a Maintenance Relapse Setting
Cancers·2022· 20 citedOpen Access
Abstract CT191: A window-of-opportunity study with atezolizumab and the oncolytic virus pelareorep in early breast cancer (AWARE-1)
Cancer Research·2021· 7 cited
Abstract PS12-08: A window-of-opportunity study with atezolizumab and the oncolytic virus pelareorep in early breast cancer (REO-027, AWARE-1)
Cancer Research·2021· 3 cited
806 Changes in T cell clonality in AWARE-1 study, a window-of-opportunity study with atezolizumab and the oncolytic virus pelareorep in early breast cancer
2020· 4 citedOpen Access
Abstract OT2-09-01: A multicenter, randomized, phase II trial evaluating the efficacy of eribulin monotherapy and eribulin plus endocrine therapy in locally-recurrent or metastatic breast cancer patients after progression on endocrine therapy (REVERT study)
Cancer Research·2020
High Neutrophil-to-Lymphocyte Ratio as an Inflammatory Biomarker, is Associated with Neurological Symptoms in Carotid Artery Disease
European Journal of Vascular and Endovascular Surgery·2019
Novel Oral mTORC1/2 Inhibitor TAK-228 Has Synergistic Antitumor Effects When Combined with Paclitaxel or PI3Kα Inhibitor TAK-117 in Preclinical Bladder Cancer Models
Molecular Cancer Research·2019· 30 cited
Multicenter retrospective study to evaluate the impact of trabectedin plus pegylated liposomal doxorubicin on the subsequent treatment in women with recurrent, platinum-sensitive ovarian cancer
Anti-Cancer Drugs·2019· 10 cited
Dynamics and implications of models for intermittent androgen suppression therapy
Mathematical Biosciences & Engineering·2018· 13 citedOpen Access
KRAS mutations in the circulating free DNA (cfDNA) of non-small cell lung cancer (NSCLC) patients
Translational Lung Cancer Research·2016· 20 citedOpen Access
The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer
Clinical Cancer Research·2016· 65 cited
Abstract 3588: Emergence of multiple EGFR extracellular mutations during cetuximab treatment in colorectal cancer
Cancer Research·2015
Sym004 to circumvent resistance to cetuximab driven by emergence of EGFR extracellular mutations in colorectal cancer.
Journal of Clinical Oncology·2015
Targeting the PI3K/AKT/mTOR pathway with MLN0128 (mTORC1/2 inh) and MLN1117 (PI3K alpha inh) in bladder cancer: Rational for its testing in clinical trials.
Journal of Clinical Oncology·2015
Targeting the PI3K/AKT/mTOR pathway with MLN0128 (mTORC1/2 inh) and MLN1117 (PI3K alpha inh) in bladder cancer: Rational for its testing in clinical trials.
Journal of Clinical Oncology·2015· 2 cited
Emergence of Multiple <i>EGFR</i> Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer
Clinical Cancer Research·2015· 266 citedOpen Access
Evolution of heterogeneous mechanisms of acquired resistance to cetuximab-based therapy in colorectal cancer.
Journal of Clinical Oncology·2014· 6 cited
P-068 Trisomy 8 in de novo MDS, constitutional or not constitutional?
Leukemia Research·2013
Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer
Journal of Thoracic Oncology·2010· 158 citedOpen Access
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Frequent Co-authors

Ana Rovira(9), Beatríz Bellosillo(8), Joan Albanell(8), Joaquim Bellmunt(6), Israel Cañadas(5), Elena Gavilán(5), Alba Dalmases(5), Clara Montagut(5), Oriol Arpí(5), Mar Iglesias(4), Marta Salido(4), Sabrina Arena(3), Giulia Siravegna(3), Iria González(3), Alberto Bardelli(3), Sílvia Menéndez(3), Natalia Iarchouk(3), Federico Rojo(3), Rachael Brake(3), Luís Manso(3)