Abigail Wynne

University College London — United Kingdom

Medicine · Health Sciences

10h-index1.0kcitations18works0.02yr avg
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Research Topics

Cardiac Ischemia and Reperfusion(10), Cardiac Arrest and Resuscitation(5), Cardiovascular Function and Risk Factors(5), Adipokines, Inflammation, and Metabolic Diseases(4), Regulation of Appetite and Obesity(3)

Publications18 total

Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner
Cardiovascular Diabetology·2013· 96 citedOpen Access
Glimepiride Treatment Facilitates Ischemic Preconditioning in the Diabetic Heart
Journal of Cardiovascular Pharmacology and Therapeutics·2012· 33 citedOpen Access
Failure of the Adipocytokine, Resistin, to Protect the Heart From Ischemia-Reperfusion Injury
Journal of Cardiovascular Pharmacology and Therapeutics·2010· 13 citedOpen Access
Leptin-induced cardioprotection involves JAK/STAT signaling that may be linked to the mitochondrial permeability transition pore
American Journal of Physiology-Heart and Circulatory Physiology·2010· 108 citedOpen Access
Ischaemic Preconditioning and Postconditioning do not Affect Adenosine A1 and A2A Receptor Sensitivity
Cardiovascular Drugs and Therapy·2009· 4 citedOpen Access
Preconditioning the diabetic human myocardium
Journal of Cellular and Molecular Medicine·2009· 81 citedOpen Access
The Cardioprotective Actions of Leptin Are Lost in the Zucker Obese (fa/fa) Rat
Journal of Cardiovascular Pharmacology·2009· 24 cited
The adipocytokine, resistin, is not cardioprotective despite activating components of the risk pathway
Journal of Molecular and Cellular Cardiology·2008
Over-expression of the cardioprotective kinase Akt modulates mitochondrial morphology
Journal of Molecular and Cellular Cardiology·2008
Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening
Basic Research in Cardiology·2007· 204 cited
Temporal Changes in Myocardial Salvage Kinases During Reperfusion Following Ischemia: Studies Involving the Cardioprotective Adipocytokine Apelin
Cardiovascular Drugs and Therapy·2007· 52 cited
Apelin, the potentially therapeutic adipocytokine, protects against myocardial ischemia–reperfusion injury
Journal of Molecular and Cellular Cardiology·2007· 1 cited
Reperfusion signaling in preconditioned hearts: Role for Pkc, The Mkatp channel, oxidative stress and transient acidosis
Journal of Molecular and Cellular Cardiology·2007
The metabolic syndrome raises the threshold for cardioprotection
Journal of Molecular and Cellular Cardiology·2007· 3 cited
Glimepiride reduces the threshold for ischemic preconditioning in the diabetic heart
Journal of Molecular and Cellular Cardiology·2007· 3 cited
Leptin, the obesity-related adipocytokine, protects the myocardium against ischaemia–reperfusion injury
Journal of Molecular and Cellular Cardiology·2006
Pioglitazone Mimics Preconditioning in the Isolated Perfused Rat Heart
Journal of Cardiovascular Pharmacology·2005· 60 cited
Transient Mitochondrial Permeability Transition Pore Opening Mediates Preconditioning-Induced Protection
Circulation·2004· 351 citedOpen Access

Frequent Co-authors

Derek M. Yellon(17), Derek J. Hausenloy(13), Mihaela Mocanu(9), Sean M. Davidson(8), Christopher Smith(7), Richard A. F. Dixon(3), Vivek Sivaraman(3), James Simpkin(3), Louise Theodorou(2), Niels P. Riksen(2), Shiang Y. Lim(2), Michael R. Duchen(1), Gurpreet S. Bhamra(1), Richard D. Carr(1), Marta Paiva(1), Sang‐Ging Ong(1), Sapna Subrayan(1), Hannah J. Whittington(1), Shah S Begum(1), Michaela M. Mocanu(1)