Vassiliki Poulaki

Massachusetts Eye and Ear Infirmary — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

39h-index9.9kcitations65works0.02yr avg

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Research Topics

Cell death mechanisms and regulation(19), Retinal Diseases and Treatments(16), Cancer-related Molecular Pathways(10), Glaucoma and retinal disorders(8), Multiple Myeloma Research and Treatments(8)

Publications64 total

Editorial Expression of Concern: Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

Oncogene·2024Open Access

Loss of ABCB5 leads to progressive visual loss due to sphingolipid accumulation in Retinal Pigment Epithelium

2017

Bromodomain (BRD) inhibition as a novel strategy to inhibit the Microphthalmia-associated transcription factor (MITF) axis in uveal melanoma (UM)

Investigative Ophthalmology & Visual Science·2015

Sensitivity and Resistance of Uveal Melanoma (UM) cells to PKC inhibition: Role of the Steroid Receptor Coactivator (SRC)-3

Investigative Ophthalmology & Visual Science·2014

Protein Kinase C Inhibitors Sensitize<i>GNAQ</i>Mutant Uveal Melanoma Cells to Ionizing Radiation

12 cited

Investigative Ophthalmology & Visual Science·2014· 12 citedOpen Access

Microphthalmia-associated transcription factor (MITF) and Steroid Receptor Coactivator (SRC)-3 cooperate to promote proliferation, survival and metabolism in Gα-mutant uveal melanoma (UM) cells

Investigative Ophthalmology & Visual Science·2013

The Protein Kinase C (PKC)/Protein Kinase D (PKD)/Steroid Receptor Coactivator (SRC)-3 pathway is an important therapeutic target in Gα-mutant Uveal Melanomas

1 cited

Investigative Ophthalmology & Visual Science·2012· 1 cited

Genotype-Dependent Sensitivity of Uveal Melanoma Cell Lines to Inhibition of B-Raf, MEK, and Akt Kinases: Rationale for Personalized Therapy

47 cited

Investigative Ophthalmology & Visual Science·2011· 47 citedOpen Access

Genotype-Dependent Sensitivity Of Ocular Melanoma Cell Lines To Inhibitors Of Kinases, Including BRAF, MEK And Akt: Rationale For Personalized Therapy

Investigative Ophthalmology & Visual Science·2011

Retinal Vascular Permeability in Health and Disease

1 cited

Frontiers in diabetes·2009· 1 cited

Role of α4 Integrin (CD49d) in the Pathogenesis of Diabetic Retinopathy

57 cited

Investigative Ophthalmology & Visual Science·2009· 57 cited

Molecular Sequelae of Histone Deacetylase Inhibition in Human Retinoblastoma Cell Lines: Clinical Implications

17 cited

Investigative Ophthalmology & Visual Science·2009· 17 cited

TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations.

227 cited