Lih-Ling Lin

Pfizer (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index2.0kcitations21works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(4), Bacterial Genetics and Biotechnology(3), Immune Response and Inflammation(3), Cytokine Signaling Pathways and Interactions(3), NF-κB Signaling Pathways(3)

Publications21 total

Subsets of ILC3−ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues
Nature Immunology·2019· 190 citedOpen Access
Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling
Journal of Biological Chemistry·2018· 44 citedOpen Access
SAT0024 Epigenetic Analysis of Lps-Induced Tolerance in Rheumatoid Arthritis Synovial Fibroblasts and Macrophages
Annals of the Rheumatic Diseases·2016
Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway
Scientific Reports·2015· 68 citedOpen Access
OP0110 Bet Bromodomain Proteins Regulate the Matrix Degrading and Inflammatory Properties of Rheumatoid Arthritis Synovial Fibroblasts
Annals of the Rheumatic Diseases·2014· 2 cited
AB0032 Toll-like receptor stimulation induces tolerizable and non-tolerizable effects in rheumatoid arthritis synovial fibroblasts
Annals of the Rheumatic Diseases·2013· 1 cited
The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls
Genome Medicine·2012· 32 citedOpen Access
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines
Lara D. Veeken·2009· 90 cited
Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1
2009
Identification of a Novel Human Kinase Supporter of Ras (hKSR-2) That Functions as a Negative Regulator of Cot (Tpl2) Signaling
Journal of Biological Chemistry·2003· 48 citedOpen Access
Solution structure of the tumor necrosis factor receptor-1 death domain
Journal of Molecular Biology·2001· 47 cited
Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-111Edited by P. E. Wright
Journal of Molecular Biology·2000· 36 cited
Solution Structure of N-TRADD and Characterization of the Interaction of N-TRADD and C-TRAF2, a Key Step in the TNFR1 Signaling Pathway
Molecular Cell·2000· 54 citedOpen Access
Protein kinase C ε-dependent pathway of extracellular signal-regulated protein kinase activation by P2Y1 and P2Y2 purinoceptors that activate cytosolic phospholipase A2 in endothelial cells
European Journal of Pharmacology·1999· 18 cited
Calcium-mediated Translocation of Cytosolic Phospholipase A2 to the Nuclear Envelope and Endoplasmic Reticulum
Journal of Biological Chemistry·1995· 469 citedOpen Access
[20] Cleavage of LexA repressor
Methods in enzymology on CD-ROM/Methods in enzymology·1994· 58 cited
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.
Proceedings of the National Academy of Sciences·1992· 544 citedOpen Access
Phospholipase C-gamma 1 association with CD3 structure in T cells.
The Journal of Experimental Medicine·1992· 56 citedOpen Access
Platelet-derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2.
Molecular and Cellular Biology·1991· 86 citedOpen Access
Autodigestion and RecA-dependent cleavage of Ind− mutant LexA proteins
Journal of Molecular Biology·1989· 87 cited
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Frequent Co-authors

John W. Little(3), Sang Hsu(3), Guang-Yi Xu(3), Kerstin Klein(3), Caroline Ospelt(3), John L. Knopf(2), Scott A. Jelinsky(2), Margot O’Toole(2), Jean-Baptiste Telliez(2), Karl Malakian(2), Steven F. Sukits(2), Robert Powers(2), Christoph Kolling(2), Augustine Y. Lin(1), Andrea R. Schievella(1), Martha K. Regier(1), William L. Smith(1), Marina Cella(1), Ramya Gamini(1), Cristiane Sécca(1)