Ludovic Bourré

Angiocrine Bioscience (United States) — United States

Medicine · Health Sciences

18h-index1.1kcitations75works1.02yr avg
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Research Topics

Photodynamic Therapy Research Studies(26), Nanoplatforms for cancer theranostics(21), Porphyrin and Phthalocyanine Chemistry(13), Cancer, Hypoxia, and Metabolism(8), Cancer Research and Treatments(8)

Publications75 total

714 Humanized engineered syngeneic mouse models for ADC/IO combination evaluation
Regular and Young Investigator Award Abstracts·2025Open Access
Abstract B094: Modelling ADC sensitivity and mode-of-action in human cancer derived organoids
Molecular Cancer Therapeutics·2025
Abstract A044: Characterization of DS8201 (Enhertu) in a Clinically Pretreated NSCLC Patient-Derived Xenograft (PDX) Model
Molecular Cancer Therapeutics·2025
Abstract B058: Antitumor activity and bystander killing effect of HER2 antibody-drug conjugates (ADCs) against tumors with different HER2 expression levels
Molecular Cancer Therapeutics·2025
Abstract 1272: The development of PDX models from ADC-resistant breast cancer patient tissue for next-generation therapy evaluation
Cancer Research·2025
Abstract 7270: Novel humanized cell and murine models expressing tumor-associated antigens for ADC toxicity and IO combination evaluation
Cancer Research·2025
Abstract 418: Modelling PARP inhibitor resistance using CRISPR/Cas9 genome engineering in a PARP inhibitor-sensitive organoid model identified by organoid panel screening
Cancer Research·2025
Abstract 5524: Developing KRASG12C inhibitor-resistant tumor models for efficacy evaluation of next-generation anticancer therapies
Cancer Research·2025
Abstract 5493: 3D bone marrow niche: Scalable and physiologically relevant <i>ex vivo</i> drug screening platform for acute myeloid leukemia and multiple myeloma
Cancer Research·2025
Abstract 7335: Comparison of ADCC-mediated efficacy of zolbetuximab in hCD16A-CB17SCID humanized mice and CB17SCID WT mice bearing the SNU-601 tumor model
Cancer Research·2025
Abstract 5195: Development of paired PDX-PDXO preclinical models for HER2-targeting ADC efficacy evaluation
Cancer Research·2025
Abstract 5497: Sacituzumab govitecan screening in a large organoid panel reveals the importance of functional assays for predicting ADC tumor response
Cancer Research·2025
275 (PB263): Osimertinib resistant NSCLC Patient derived xenograft model mimic clinical response status of multiple TKI treatments in preclinical study
European Journal of Cancer·2024
274 (PB262): Development of Patient-Derived Colorectal Cancer Xenograft and Organoid Models with Acquired Resistance to KRAS G12C Inhibitors
European Journal of Cancer·2024
169 (PB157): Large-Scale ADC Efficacy Testing in an Organoid Drug Screening Platform Highlights the Need for Functional Assays to Predict Tumor Sensitivity
European Journal of Cancer·2024
INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death
Oncotarget·2024· 14 citedOpen Access
Abstract LB435: Large panel organoid drug testing combined with biomarker analysis: Unveiling prospects for mechanism of action identification and preclinical patient stratification
Cancer Research·2024· 2 cited
Abstract 5264: KRASG12C inhibition synergizes with checkpoint blockade in KRASG12C-mutated tumor model
Cancer Research·2024
Abstract 1942: Characterization of a panel of CRISPR/Cas9 engineered KRAS G12C inhibitor-resistant tumor models
Cancer Research·2024
Abstract 2827: Characterization of acute myeloid leukemia PDX models with hotspot gene mutations for therapeutic evaluation
Cancer Research·2024
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Frequent Co-authors

Thierry Patrice(13), Y. Lajat(9), Nathalie Rousset(8), Sonia Thibaut(7), Ian M. Eggleston(7), Sabine Eléouet(6), Francesca Giuntini(6), Alexander J. MacRobert(6), Gérard Simonneaux(5), T. Patrice(4), David Olivier(4), Marrit Putker(4), Caitríona M. O’Driscoll(3), Michael Wilson(3), Jérôme Carré(3), Véronique Vonarx(3), Marten Hornsveld(3), Jinxi Wang(3), Silvia Melgar(2), Amélie Briffaud(2)