Takehiko Nohmi

National Institute of Health Sciences — LK

Biochemistry, Genetics and Molecular Biology · Life Sciences

48h-index10.2kcitations321works1.82yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(169), DNA Repair Mechanisms(155), CRISPR and Genetic Engineering(40), DNA and Nucleic Acid Chemistry(38), Bacterial Genetics and Biotechnology(27)

Publications321 total

Mitomycin C-induced DNA double-strand breaks are enhanced by catalytical inactivation of DNA polymerase κ in mice
Genes and Environment·2025Open Access
Oxidative stress accelerates repeat sequence instability and base substitutions promoting gastrointestinal driver mutations in MSH2 deficient mice
Genes and Environment·2025Open Access
Oxidative Stress Accelerates Repeat Instability and Base Substitutions, Promoting Gastrointestinal Driver Mutations under MSH2 Deficiency
2025Open Access
Homology-arm length of donor DNA affects the impact of Msh2 loss on homologous recombination–mediated gene targeting
Proceedings of the National Academy of Sciences·2025Open Access
Possible contribution of 8-hydroxydeoxyguanosine to gene mutations in the kidney DNA of gpt delta rats following potassium bromate treatment
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2024· 2 cited
Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice
Genome Research·2024· 9 citedOpen Access
Site-specific genotoxicity of rubiadin: localization and histopathological changes in the kidneys of rats
Archives of Toxicology·2023
DNA polymerase κ suppresses inflammation and inflammation-induced mutagenesis and carcinogenic potential in the colon of mice
Genes and Environment·2023· 3 citedOpen Access
Supplementary Table 2 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 4 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 1 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 3 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Data from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Data from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 1 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 3 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 4 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Supplementary Table 2 from Enhanced Spontaneous and Benzo(<i>a</i>)pyrene-Induced Mutations in the Lung of Nrf2-Deficient <i>gpt</i> Delta Mice
2023Open Access
Additional file 1 of DNA polymerase κ suppresses inflammation and inflammation-induced mutagenesis and carcinogenic potential in the colon of mice
Figshare·2023Open Access
Comprehensive analysis of the general toxicity, genotoxicity, and carcinogenicity of 3-acetyl-2,5-dimethylfuran in male gpt delta rats
Food and Chemical Toxicology·2022· 7 cited
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Frequent Co-authors

Petr Grúz(9), Masami Yamada(9), Kenichi Masumura(8), Masahiko Watanabe(7), Su-Ryang Kim(6), Toshio Sofuni(5), Motoi Ishidate(5), Akiyoshi Nishikawa(5), Takashi Umemura(4), Errol C. Friedberg(3), Robert P. Fuchs(3), Fumio Hanaoka(3), Jérôme Wagner(3), Keiko Matsui(3), Takashi Kohno(3), Kazuya Shinmura(3), Yoshimitsu Oda(3), Masatomi Shimizu(3), Haruo Ohmori(2), Masachika Tani(2)