S. -H. Yen

Medicine · Health Sciences

22h-index2.1kcitations38works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(17), Neurological diseases and metabolism(7), Parkinson's Disease Mechanisms and Treatments(6), Prion Diseases and Protein Misfolding(6), Glycosylation and Glycoproteins Research(4)

Publications37 total

Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene
Brain·2002· 121 citedOpen Access
Pathogenic Implication of Altered Tau Properties Caused by FTDP‐17 Mutations
2001
Sensitization of Neuronal Cells to Oxidative Stress with Mutated Human α‐Synuclein
Journal of Neurochemistry·2000· 87 cited
FTDP-17 mutations of tau have multiple effects on its biochemical and physiochemical properties
Neurobiology of Aging·2000
A novel approach for nasopharyngeal carcinoma treatment uses phenylbutyrate as a protein kinase C modulator: implications for radiosensitization and EBV-targeted therapy.
PubMed·2000· 31 cited
Missense tau mutations identified in FTDP-17 have a small effect on tau–microtubule interactions
Brain Research·2000· 81 cited
Missense and Splice Site Mutations in Tau Associated with FTDP-17 Multiple Pathogenic Mechanisms
Research and perspectives in Alzheimer's disease·2000· 6 cited
FTDP‐17 tau mutations decrease the susceptibility of tau to calpain I digestion
FEBS Letters·1999· 43 citedOpen Access
WIDESPREAD ALTERATIONS IN ALPHA-SYNUCLEIN IN MULTIPLE SYSTEM ATROPHY
Journal of Neuropathology & Experimental Neurology·1999· 12 cited
ACCELERATED FILAMENT FORMATION FROM TAU PROTEIN WITH SPECIFIC FTDP-17 MISSENSE MUTATIONS
Journal of Neuropathology & Experimental Neurology·1999· 12 cited
Serum responses to the combination of Epstein-Barr virus antigens from both latent and acute phases in nasopharyngeal carcinoma: complementary test of EBNA-1 with EA-D.
PubMed·1997· 20 cited
AN ANTIBODY TO A SYNTHETIC PEPTIDE WITH AN AMINO ACID SEQUENCE IDENTICAL TO AN AMINO-TERMINAL REGION OF PRESENILIN-1 IMMUNOSTAINS NEUROFIBRILLARY TANGLES IN ALZHEIMERʼS DISEASE (AD)
Journal of Neuropathology & Experimental Neurology·1996
Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments
Journal of Neuroscience Research·1995· 24 cited
Epitope expression and hyperphosphorylation of tau protein in corticobasal degeneration: differentiation from progressive supranuclear palsy
Acta Neuropathologica·1995· 2 cited
REVERSIBLE HEAT STRESS-RELATED LOSS OF PHOSPHORYLATED ALZHEIMER TYPE EP1TOPES IN TAU PROTEINS OF HUMAN NEUROBLASTOMA CELLS
Journal of Neuropathology & Experimental Neurology·1993
Immunocytochemistry of neurofibrillary tangles with antibodies to subregions of tau protein: identification of hidden and cleaved tau epitopes and a new phosphorylation site
Acta Neuropathologica·1992· 75 cited
Neurofibrillary degeneration and microtubule associated protein tau.
PubMed·1992
The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments.
PubMed·1991· 30 citedOpen Access
Argyrophilic ubiquitinated cytoplasmic inclusions of Leu-7-positive glial cells in olivopontocerebellar atrophy (multiple system atrophy)
Acta Neuropathologica·1991· 79 cited
Microglia in cerebellar plaques in Alzheimer's disease
Acta Neuropathologica·1990· 108 cited
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Frequent Co-authors

Dennis W. Dickson(16), Hanna Ksiȩżak-Reding(12), Peter Davies(6), Colin Easson(6), Alex Crowe(5), Parimala Nacharaju(5), M. Hutton(3), Stuart Pickering‐Brown(2), John Hardy(2), Li‐wen Ko(2), Shu‐Hui Yen(2), Michael DeTure(2), Jada Lewis(2), Michael Hutton(2), Shu-Hui Yen(2), Atsushi Hirano(2), Josefina F. Llena(2), Bridget Shafit‐Zagardo(2), J. Farlo(1), Howard Crystal(1)