Frank A. DeLano

University of California, San Diego — United States

Medicine · Health Sciences

20h-index1.9kcitations60works2.02yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(10), Cell Adhesion Molecules Research(7), Protease and Inhibitor Mechanisms(5), Pancreatic function and diabetes(5), Coagulation, Bradykinin, Polyphosphates, and Angioedema(5)

Publications60 total

Aging by autodigestion
PLoS ONE·2024· 2 citedOpen Access
Continuous enteral protease inhibition as a novel treatment for experimental trauma/hemorrhagic shock
European Journal of Trauma and Emergency Surgery·2021· 9 citedOpen Access
Screening for Surgical Acute Abdomen Using Exhaled Breath Analysis
Journal of the American College of Surgeons·2018
Volatile Decay Products in Breath During Peritonitis Shock are Attenuated by Enteral Blockade of Pancreatic Digestive Proteases
Shock·2017· 10 citedOpen Access
Protease Inhibition to Optimize the Intestinal Mucosal Barrier to Digestive Enzymes during Hemorrhagic Shock
The FASEB Journal·2017
172: ENTERAL PROTEASE INHIBITION IN TRAUMA/HEMORRHAGIC SHOCK: EFFECTS ON BIOCHEMICAL PARAMETERS
Critical Care Medicine·2016
Cathepsin Localization and Activity on the Intestinal Epithelial Barrier of Rats following Hemorrhagic Shock and Reperfusion
The FASEB Journal·2016
Peptidomic Analysis of Rat Plasma
Shock·2015· 28 citedOpen Access
Pancreatic Digestive Enzyme Blockade in the Small Intestine Prevents Insulin Resistance in Hemorrhagic Shock
Shock·2013· 18 cited
Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock
Science Translational Medicine·2013· 73 cited
Receptor cleavage and P-selectin-dependent reduction of leukocyte adhesion in the spontaneously hypertensive rat
Journal of Leukocyte Biology·2012· 18 citedOpen Access
Evaluation Of Volatile Markers In Patients With Severe Sepsis Or Septic Shock And Healthy Volunteers
2012
Analyse des composants volatils expirés après occlusion aiguë de l'artère mésentérique supérieure dans une étude pilote chez le rat
Annales de Chirurgie Vasculaire·2011
Analysis of Exhaled Volatile Compounds Following Acute Superior Mesenteric Artery Occlusion in a Pilot Rat Study
Annals of Vascular Surgery·2011· 7 citedOpen Access
Matrix Metalloproteinase Activity Causes VEGFR‐2 Cleavage and Microvascular Rarefaction in Rat Mesentery
Microcirculation·2011· 20 citedOpen Access
Receptor cleavage reduces the fluid shear response in neutrophils of the spontaneously hypertensive rat
American Journal of Physiology-Cell Physiology·2010· 33 citedOpen Access
Adrenergic innervation of skeletal muscle arterioles
Journal of the American College of Surgeons·2010
Enteral and peritoneal blockade of serine proteolytic enzymes accelerates post-surgical bowel function recovery
Journal of the American College of Surgeons·2010
Inflammatory Markers in Isolated Endothelial Cells of the Spontaneously Hypertensive Rat
The FASEB Journal·2010
PROTEOLYTIC CLEAVAGE OF INSULIN RECEPTOR BY PANCREATIC DIGESTIVE ENZYMES LEADS TO INSULIN RESISTANCE IN HEMORRHAGIC SHOCK
The FASEB Journal·2010· 1 cited
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Frequent Co-authors

Geert W. Schmid‐Schönbein(26), Geert W. Schmid‐Schönbein(23), Edward D. Tran(6), Benjamin W. Zweifach(4), Florian Fitzal(4), Corey Young(4), Dale A. Parks(3), Makoto Suematsu(3), L. Lerond(3), Darin J. Saltzman(3), Hidekazu Suzuki(2), Neema Jamshidi(2), Hiromasa Ishii(2), ALLEN SWEI(2), FRED LACY(2), David B. Hoyt(2), John J. Bergan(2), Henrique Rosario(2), Jessica N. Ha(2), Federico Aletti(2)