Leo Hofstra

Biochemistry, Genetics and Molecular Biology · Life Sciences

37h-index4.6kcitations85works0.02yr avg
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Research Topics

S100 Proteins and Annexins(27), Cell death mechanisms and regulation(22), Cardiovascular Health and Disease Prevention(8), Phagocytosis and Immune Regulation(8), Central Venous Catheters and Hemodialysis(7)

Publications85 total

Association of Mild Kidney Dysfunction with Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction
ESC Heart Failure·2023· 12 citedOpen Access
SMILE and HAPPY: Novel Public Programs for Preventive Cardiology
MD Conference Express·2013
Epicardial adipose tissue volume as a predictor for coronary artery disease in diabetic, impaired fasting glucose, and non-diabetic patients presenting with chest pain
European Heart Journal - Cardiovascular Imaging·2012· 48 citedOpen Access
Visualization of Cell Death in MICE with Focal Cerebral Ischemia using Fluorescent Annexin A5, Propidium Iodide, and Tunel Staining
Journal of Cerebral Blood Flow & Metabolism·2011· 40 citedOpen Access
Moderately impaired renal function is a predictor of increased coronary plaque burden in patients with suspected coronary artery disease
2011
Noninvasive Imaging of Carotid Atherosclerosis
2010
The electrocardiogram of a man found in the forest.
PubMed·2010· 1 cited
Site-specific labeling of 'second generation' annexin V with Tc-99m(CO)(3) for improved imaging of apoptosis in vivo
Research Publications (Maastricht University)·2010· 39 citedOpen Access
Syndecan-1 Amplifies Angiotensin II–Induced Cardiac Fibrosis
Hypertension·2010· 72 citedOpen Access
Myocardial remodeling after infarction: the role of myofibroblasts
Nature Reviews Cardiology·2009· 734 citedOpen Access
Transfection efficiency of lipoplexes for site-directed delivery
Journal of Liposome Research·2009· 9 cited
Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis
Journal of Nuclear Cardiology·2009· 57 citedOpen Access
Hypoxia Induces Dilated Cardiomyopathy in the Chick Embryo: Mechanism, Intervention, and Long-Term Consequences
PLoS ONE·2009· 140 citedOpen Access
PET and SPECT imaging of apoptosis in vulnerable atherosclerotic plaques with radiolabeled Annexin A5.
PubMed·2009· 51 cited
Macrophage Depletion in Hypertensive Rats Accelerates Development of Cardiomyopathy
Journal of Cardiovascular Pharmacology and Therapeutics·2009· 59 citedOpen Access
Identifying vulnerable carotid plaques by noninvasive imaging
Neurology·2008· 69 cited
Imaging Highlights of the American Heart Association 2007 Scientifıc Sessions
JACC. Cardiovascular imaging·2008· 1 cited
Extracellular annexin A5: Functions of phosphatidylserine-binding and two-dimensional crystallization
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2008· 227 cited
Broad and Specific Caspase Inhibitor-Induced Acute Repression of Apoptosis in Atherosclerotic Lesions Evaluated by Radiolabeled Annexin A5 Imaging
Journal of the American College of Cardiology·2007· 61 cited
Non invasive in vivo mu SPECT imaging of apoptosis and necrosis in rabbits with a novel site specific Tc-99m-labelled annexin-A5-HYNIC derivative and mono[I-123] iodohypericin after acute reperfused myocardial infarction
European Journal of Nuclear Medicine and Molecular Imaging·2007
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Frequent Co-authors

Chris Reutelingsperger(27), Jagat Narula(12), Heidi Kenis(8), G. A. K. Heidendal(7), Hendrikus H. Boersma(6), Peter J.E.H.M. Kitslaar(6), Frank D. Kolodgie(5), Artiom Petrov(5), Renu Virmani(5), Navneet Narula(5), Dagmar Hartung(5), Jagat Narula(5), Niko Deckers(5), Johan Verjans(4), Ing Han Liem(4), Gerrit J. Kemerink(4), Mat J.A.P. Daemen(4), Hugo van Genderen(4), Harry J.G.M. Crijns(4), Karel M.L. Leunissen(4)