Mohamed Abdel‐Aziz

Minia University — Egypt

Chemistry · Physical Sciences

34h-index3.7kcitations129works6.92yr avg
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Research Topics

Synthesis and biological activity(91), Synthesis and Biological Evaluation(34), Synthesis and Characterization of Heterocyclic Compounds(26), Quinazolinone synthesis and applications(21), Cancer therapeutics and mechanisms(20)

Publications129 total

Design, synthesis, and apoptotic antiproliferative action of new styryl benzimidazole-based derivatives as dual EGFR/BRAFV600E inhibitors
Journal of Molecular Structure·2025
Design, Synthesis, and Biological Evaluation of Novel Benzimidazole/Schiff Base Hybrid Derivatives With Potential Biological Activities
Archiv der Pharmazie·2025
Biologically Active Benzimidazole Hybrids as Cancer Therapeutics: Recent Advances
Pharmaceuticals·2025· 2 citedOpen Access
Design, synthesis, and biological evaluation of novel 1,5-diarylpyrazole carboxamides with dual inhibition of EGFR and COX-2 for the treatment of cancer and inflammatory diseases
Bioorganic & Medicinal Chemistry Letters·2025· 1 cited
Targeting melanoma resistance: Novel oxindole and non-oxindole-based benzimidazole derivatives as potent dual inhibitors of BRAFV600E and ABL2 kinases
European Journal of Medicinal Chemistry·2025
Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation
European Journal of Medicinal Chemistry·2025· 1 cited
Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors
Frontiers in Chemistry·2025· 5 citedOpen Access
New antiproliferative 1,3,4-oxadiazole/benzimidazole derivatives: Design, synthesis, and biological evaluation as dual EGFR and BRAFV600E inhibitors
Bioorganic Chemistry·2025· 7 cited
Amidoximes and their Cyclized Analogue Oxadiazoles as New Frontiers in Chemical Biology: Mini Review
Letters in Drug Design & Discovery·2024· 2 cited
An overview of the most used synthetic pathways of 1,2,4-triazolo[1,5-a]pyrimidines
Results in Chemistry·2024· 2 citedOpen Access
Investigation of anticancer mechanisms of a chalcone/xanthine hybrid in Non-Small Cell Lung Cancer
Bulletin of Pharmaceutical Sciences Assiut·2024Open Access
Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR-2 Inhibitors
ACS Omega·2024· 27 citedOpen Access
Benzimidazole scaffold as a potent anticancer agent with different mechanisms of action (2016–2023)
Molecular Diversity·2024· 23 citedOpen Access
Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition
Frontiers in Chemistry·2024· 11 citedOpen Access
New Ciprofloxacin–Pyrazolopyrimidine Hybrids as Topoisomerase IV and Gyrase Inhibitors against <i>MRSA AUMC 261</i>
ChemistrySelect·2024· 3 cited
Ligand-based design and synthesis of new trityl histamine and trityl cysteamine derivatives as SIRT2 inhibitors for cancer therapy
European Journal of Medicinal Chemistry·2024· 5 citedOpen Access
Development of 1,5-diarylpyrazoles as EGFR/JNK-2 dual inhibitors: design, synthesis, moleecular docking, and bioactivity evaluation
Bioorganic & Medicinal Chemistry Letters·2024· 5 citedOpen Access
Quinazoline‐chalcone hybrids as HDAC/EGFR dual inhibitors: Design, synthesis, mechanistic, and in‐silico studies of potential anticancer activity against multiple myeloma
Archiv der Pharmazie·2024· 13 cited
Benzimidazole-Based Derivatives as Apoptotic Antiproliferative Agents: Design, Synthesis, Docking, and Mechanistic Studies
Molecules·2024· 25 citedOpen Access
Design and synthesis of new quinoline-ester/-amide derivatives as potent antiproliferative agent targeting EGFR and BRAFV600E kinases
Journal of Molecular Structure·2023· 16 cited
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Frequent Co-authors

Gamal El‐Din A. Abuo‐Rahma(19), Bahaa G. M. Youssif(17), Dalia Abdelhamid(10), Heba A. Hassan(8), Hamdy M. Abdel‐Rahman(7), Samar H. Abbas(7), Tamer S. Kaoud(6), Mohamed Ramadan(6), Alaa M. Hayallah(5), Aliaa M. Mohassab(5), Ahmed M. Gouda(5), Eman A. M. Beshr(5), Hesham A. M. Gomaa(5), Syed Nasir Abbas Bukhari(4), Taha F. S. Ali(4), Hassan H. Farag(4), Hany A.M. El-Sherief(3), Mai E. Shoman(3), Salah A. Abdel‐Aziz(3), Elshimaa M. N. Abdelhafez(3)