Sylvia Y.M. Yao

Pennsylvania State University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

32h-index5.3kcitations71works2.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Adenosine and Purinergic Signaling(46), Drug Transport and Resistance Mechanisms(15), Amino Acid Enzymes and Metabolism(15), HIV/AIDS drug development and treatment(12), Pharmacological Effects and Toxicity Studies(12)

Publications71 total

Biological effects of graphene oxide-induced fluorescent marker perturbation in Caenorhabditis elegans via food chain exposure
Ecotoxicology and Environmental Safety·2025· 2 citedOpen Access
Evaluating Major Bleeding Risks with Concomitant Use of Direct Oral Anticoagulants and Selective Serotonin Reuptake Inhibitors in Nonvalvular Atrial Fibrillation Patients
Pharmacoepidemiology·2025Open Access
A conformational switch-controlled RNA sensor based on orthogonal dCas12a for RNA imaging in live cells
Biosensors and Bioelectronics·2025· 4 cited
HPLC reveals novel features of nucleoside and nucleobase homeostasis, nucleoside metabolism and nucleoside transport
Biochimica et Biophysica Acta (BBA) - Biomembranes·2020· 18 cited
<i>In vitro</i> inhibition of human nucleoside transporters and uptake of azacitidine by an isocitrate dehydrogenase-2 inhibitor enasidenib and its metabolite AGI-16903
Xenobiotica·2018· 1 cited
Role of cysteine 416 in<i>N</i>-ethylmaleimide sensitivity of human equilibrative nucleoside transporter 1 (hENT1)
Biochemical Journal·2018· 6 cited
Inward- and outward-facing homology modeling of human concentrative nucleoside transporter 3 (hCNT3) predicts an elevator-type transport mechanism
Channels·2018· 7 citedOpen Access
SLC28 and SLC29
2017
Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance
Journal of Biological Chemistry·2017· 13 citedOpen Access
SLC28 and SLC29
2017
Synthesis of Purine and 7‐Deazapurine Nucleoside Analogues of 6‐<i>N</i>‐(4‐Nitrobenzyl)adenosine; Inhibition of Nucleoside Transport and Proliferation of Cancer Cells
ChemMedChem·2014· 13 citedOpen Access
The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29
Molecular Aspects of Medicine·2013· 340 citedOpen Access
Human Concentrative Nucleoside Transporter 3 Transfection with Ultrasound and Microbubbles in Nucleoside Transport Deficient HEK293 Cells Greatly Increases Gemcitabine Uptake
PLoS ONE·2013· 32 citedOpen Access
Transport of A1 Adenosine Receptor Agonist Tecadenoson by Human and Mouse Nucleoside Transporters: Evidence for Blood-Brain Barrier Transport by Murine Equilibrative Nucleoside Transporter 1 mENT1
Drug Metabolism and Disposition·2013· 11 citedOpen Access
Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses
American Journal of Physiology-Renal Physiology·2012· 71 citedOpen Access
A urea channel from <i>Bacillus cereus</i> reveals a novel hexameric structure
Biochemical Journal·2012· 9 citedOpen Access
Role of Human Nucleoside Transporters in the Uptake and Cytotoxicity of Azacitidine and Decitabine
Nucleosides Nucleotides & Nucleic Acids·2012· 62 cited
Influence of Sugar Ring Conformation on the Transportability of Nucleosides by Human Nucleoside Transporters
ChemBioChem·2011· 17 cited
Nucleobase Transport by Human Equilibrative Nucleoside Transporter 1 (hENT1)
Journal of Biological Chemistry·2011· 133 citedOpen Access
Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain
Current Topics in Medicinal Chemistry·2011· 173 cited
page 1 of 4Next →

Frequent Co-authors

James D. Young(50), Carol E. Cass(42), Stephen A. Baldwin(36), Amy M.L. Ng(25), Kyla M. Smith(12), Edward Karpinski(11), Melissa D. Slugoski(9), Manickavasagam Sundaram(7), Mark Griffiths(6), Mabel W.L. Ritzel(6), Shaun Loewen(6), Vijaya L. Damaraju(5), Kathryn Graham(4), Delores Mowles(4), Xing‐Zhen Chen(4), Ralph J. Hyde(4), Mark F. Vickers(4), Ras Mulinta(4), John R. Mackey(3), Maurice P. Gallagher(3)