Rhoda Elison Hirsch

Albert Einstein College of Medicine — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.3kcitations95works0.02yr avg
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Research Topics

Hemoglobin structure and function(68), Hemoglobinopathies and Related Disorders(34), Erythrocyte Function and Pathophysiology(24), Neonatal Health and Biochemistry(18), Heme Oxygenase-1 and Carbon Monoxide(17)

Publications95 total

Magnetic Resonance Imaging Reveals Significantly Increased Cerebral Blood Flow in the Hemoglobin E Mouse Model
Blood·2021
Decreased nitrite reductase activity of deoxyhemoglobin correlates with platelet activation in hemoglobin E/ß-thalassemia subjects
PLoS ONE·2018· 8 citedOpen Access
Oxidized Mutant Human Hemoglobins S and E Induce Oxidative Stress and Bioenergetic Dysfunction in Human Pulmonary Endothelial Cells
Frontiers in Physiology·2017· 18 citedOpen Access
HbE/β-Thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms and Novel Therapeutics
Antioxidants and Redox Signaling·2016· 43 citedOpen Access
The scientific legacy of Ronald L. Nagel (1936–2016), a true renaissance man
American Journal of Hematology·2016Open Access
Oxidative instability of hemoglobin E (β26 Glu→Lys) is increased in the presence of free α subunits and reversed by α-hemoglobin stabilizing protein (AHSP): Relevance to HbE/β-thalassemia
Redox Biology·2016· 25 citedOpen Access
Generating S-Nitrosothiols from Hemoglobin
Journal of Biological Chemistry·2013· 30 citedOpen Access
P57
Nitric Oxide·2013· 1 cited
P60
Nitric Oxide·2013
Biophysical Studies Evaluating the Potential Physiological Relevance of the Hemoglobin Associated Nitrite Anhydrase Reaction as a Pathway to Generate S-Nitrosothiols from Low Levels of NO and Nitrite
Biophysical Journal·2013Open Access
A transgenic mouse model expressing exclusively human hemoglobin E: Indications of a mild oxidative stress
Blood Cells Molecules and Diseases·2012· 10 cited
Structural and Functional Studies Indicating Altered Redox Properties of Hemoglobin E
Journal of Biological Chemistry·2011· 23 citedOpen Access
Production of Nitrosoglutathione Through Met Hemoglobin Reactions with Nitrite and Low Molecular Weight Thiols
Biophysical Journal·2011Open Access
A tribute to Seymour Steven Brody: in memoriam (November 29, 1927 to May 25, 2010)
Photosynthesis Research·2010· 8 citedOpen Access
Hemoglobin E (β26Glu→Lys) Exhibits Altered Nitrite Reactivity.
Blood·2009
High Resolution Tertiary and Quaternary Structural Changes in Deoxy and Liganded Hemoglobin E
Blood·2008
Phase Separation and Crystallization of Hemoglobin C in Transgenic Mouse and Human Erythrocytes
Biophysical Journal·2008· 9 citedOpen Access
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery
The Journal of Cell Biology·2008· 153 citedOpen Access
Two-Step Mechanism of Homogeneous Nucleation of Sickle Cell Hemoglobin Polymers
Biophysical Journal·2007· 112 citedOpen Access
Acellular Invertebrate Hemoglobins as Model Therapeutic Oxygen Carriers: Unique Redox Potentials
Artificial Cells Blood Substitutes and Biotechnology·2007· 39 cited
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Frequent Co-authors

Ronald L. Nagel(21), Joel M. Friedman(9), Peter G. Vekilov(8), John P. Harrington(6), Qiuying Chen(6), Margaret Lin(6), Oleg Galkin(5), Nazim A. Fataliev(5), Laura J. Juszczak(4), Eric E. Bouhassira(3), Angela R. Feeling-Taylor(3), R L Nagel(3), Michelle Velho(2), R. Suzanne Zukin(2), Dimiter N. Petsev(2), Scott C. Dorman(2), Camille J. Roche(2), David Dantsker(2), S.‐T. Yau(2), Fantao Meng(2)