David G. Bear

Sunesis (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index5.1kcitations52works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(19), Bacterial Genetics and Biotechnology(14), Bacteriophages and microbial interactions(8), DNA and Nucleic Acid Chemistry(6), Force Microscopy Techniques and Applications(6)

Publications52 total

Abstract 160: A high-throughput in vivo platform (Perturb-map) accurately models patient immunophenotypes and identifies therapeutic targets
Cancer Research·2025
861 Multimodal foundation model of human lung tumors identifies tertiary lymphoid structures (TLS) and reveals novel therapeutic targets that promote anti-tumor immune response
Regular and Young Investigator Award Abstracts·2024Open Access
Donanemab in Early Symptomatic Alzheimer Disease
JAMA·2023· 2.2k citedOpen Access
Hip flexion weakness is associated with impaired mobility in oculopharyngeal muscular dystrophy: A retrospective study with implications for trial design
Neuromuscular Disorders·2014· 15 citedOpen Access
Student peer assessment in evidence-based medicine (EBM) searching skills training: an experiment
Journal of the Medical Library Association JMLA·2013· 28 citedOpen Access
Cationic Phenylene Ethynylene Polymers and Oligomers Exhibit Efficient Antiviral Activity
ACS Applied Materials & Interfaces·2011· 75 cited
ANALYSIS OF NUCLEOCYTOPLASMIC DISTRIBUTION OF THE ONCOPROTEIN SKIN IN HUMAN ALVEOLAR RHABDOMYOSARCOMA CELLS BY IMMUNOELECTRON MICROSCOPY.
Journal of Investigative Medicine·2007
A nanoplasmonic molecular ruler for measuring nuclease activity and DNA footprinting
Nature Nanotechnology·2006· 271 cited
Nanoplasmonic molecular ruler for nuclease activity and DNA footprinting - eScholarship
2006
Heat shock protein 70 and glycoprotein 96 are differentially expressed on the surface of malignant and nonmalignant breast cells
Cell Stress and Chaperones·2006· 39 citedOpen Access
Shear stress alters the expression of myelin‐associated glycoprotein (MAG) and myelin basic protein (MBP) in Schwann cells
Journal of Orthopaedic Research®·2005· 65 cited
Schwann cells upregulate vascular endothelial growth factor secondary to chronic nerve compression injury
Muscle & Nerve·2005· 61 citedOpen Access
93 SKI AND SNO ONCOGENE EXPRESSION IN RHABDOMYOSARCOMA.
Journal of Investigative Medicine·2004
SKI AND SNO ONCOGENE EXPRESSION IN RHABDOMYOSARCOMA.
Journal of Investigative Medicine·2004
Nuclear poly(A)-binding protein PABPN1 is associated with RNA polymerase II during transcription and accompanies the released transcript to the nuclear pore
Experimental Cell Research·2003· 54 cited
Optimization of Schwann Cell Adhesion in Response to Shear Stress in an <i>in Vitro</i> Model for Peripheral Nerve Tissue Engineering
Tissue Engineering·2003· 32 cited
Intranuclear inclusions in oculopharyngeal muscular dystrophy contain poly(A) binding protein 2
Annals of Neurology·2000· 1 cited
Intranuclear inclusions in oculopharyngeal muscular dystrophy contain poly(A) binding protein 2
Annals of Neurology·2000· 46 cited
The nuclear poly(A) binding protein, PABP2, forms an oligomeric particle covering the length of the poly(A) tail
Journal of Molecular Biology·2000· 84 cited
DNA looping by Ku and the DNA-dependent protein kinase
Proceedings of the National Academy of Sciences·1997· 250 citedOpen Access
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Frequent Co-authors

Peter H. von Hippel(11), William D. Morgan(8), Christopher L. Andrews(7), James A. McSwiggen(5), Rebecca W. Keller(4), Carlos Bustamante(4), Stephen D. Jett(3), Thomas Schleich(3), Harry F. Noller(3), Ranjan Gupta(3), J. A. Panitz(3), Gang L. Liu(2), Yadong Yin(2), Siri Kunchakarra(2), Bipasha Mukherjee(2), Daniele Gerion(2), A. Paul Alivisatos(2), Luke P. Lee(2), Fanqing Frank Chen(2), Kenneth Escudero(2)