Marianne Broome Powell

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.3kcitations41works0.02yr avg
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Research Topics

melanin and skin pigmentation(8), Melanoma and MAPK Pathways(7), Cancer, Hypoxia, and Metabolism(6), PI3K/AKT/mTOR signaling in cancer(6), Immunotherapy and Immune Responses(5)

Publications41 total

Supplementary Figures 1-2, Table 1 from Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in <i>Cdk4<sup>R24C/R24C</sup>/TPras</i> Mice
2023Open Access
Data from Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in <i>Cdk4<sup>R24C/R24C</sup>/TPras</i> Mice
2023Open Access
Data from Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in <i>Cdk4<sup>R24C/R24C</sup>/TPras</i> Mice
2023Open Access
Supplementary Figures 1-2, Table 1 from Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in <i>Cdk4<sup>R24C/R24C</sup>/TPras</i> Mice
2023Open Access
Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells
Proceedings of the National Academy of Sciences·2015· 89 citedOpen Access
TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling
Proceedings of the National Academy of Sciences·2012· 47 citedOpen Access
Abstract 3412: Hypoxia induces EMT in primary melanoma and MET in metastatic melanoma
Cancer Research·2011· 1 cited
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
Pigment Cell & Melanoma Research·2010· 66 citedOpen Access
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
Faculty of Science and Technology; Institute of Health and Biomedical Innovation·2010
Preformulation, formulation, and in vivo efficacy of topically applied Apomine
International Journal of Pharmaceutics·2009· 11 citedOpen Access
Unique transforming properties of Notch1 in human melanocytes
Pigment Cell & Melanoma Research·2009· 5 citedOpen Access
Hypoxia, melanocytes and melanoma – survival and tumor development in the permissive microenvironment of the skin
Pigment Cell & Melanoma Research·2009· 131 citedOpen Access
Notch1 is an effector of Akt and hypoxia in melanoma development
Journal of Clinical Investigation·2008· 207 citedOpen Access
Integrin A6 Cleavage in Mouse Skin Tumors
The Open Cancer Journal·2008· 4 citedOpen Access
Targeting Integrins and PI3K/Akt-Mediated Signal Transduction Pathways Enhances Radiation-Induced Anti-angiogenesis
Radiation Research·2007· 21 cited
HIF1α delays premature senescence through the activation of MIF
Genes & Development·2006· 163 citedOpen Access
Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model
Molecular Cancer Therapeutics·2006· 63 cited
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line
Investigational New Drugs·2006· 7 cited
Skin Hypoxia: A Promoting Environmental Factor in Melanomagenesis
Cell Cycle·2006· 28 citedOpen Access
Spontaneous and UV Radiation–Induced Multiple Metastatic Melanomas in <i>Cdk4R24C/R24C/TPras</i> Mice
Cancer Research·2006· 50 citedOpen Access
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Frequent Co-authors

Barbara Bedogni(9), Amato J. Giaccia(7), Elke Hacker(5), Nicole Irwin(5), Brian Gabrielli(5), Douglas Lincoln(5), Sandra Pavey(5), Marcos Malumbres(5), Mariano Barbacid(5), Nicholas K. Hayward(5), Scott M. Welford(4), G. Tim Bowden(4), Graeme M. Walker(4), Paul R. Gause(3), Maria Lluria-Prevatt(3), Alexander H. Borchers(3), Robert T. Dorr(3), David S. Alberts(3), Steven P. Stratton(3), Julie A. Buckmeier(2)