Karrie A. Brenneman

Pfizer (United States) — United States

Neuroscience · Life Sciences

17h-index1.1kcitations30works4.02yr avg
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Research Topics

Olfactory and Sensory Function Studies(5), Blood Coagulation and Thrombosis Mechanisms(4), Sulfur Compounds in Biology(4), Heavy Metal Exposure and Toxicity(3), Advanced Chemical Sensor Technologies(3)

Publications30 total

Marstacimab, an antitissue factor pathway inhibitor, combined with bypassing agents: effects on thrombin generation and in hemostatically normal rats
Research and Practice in Thrombosis and Haemostasis·2025· 1 citedOpen Access
Qualified kidney injury biomarkers demonstrate value during early clinical drug development
Toxicological Sciences·2024· 7 cited
To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System
Toxicologic Pathology·2022· 2 cited
In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency
Molecular Therapy — Methods & Clinical Development·2022· 53 citedOpen Access
Evaluation of biomarkers for monitoring thrombogenic potential of FXaI16L
Blood Coagulation & Fibrinolysis·2019· 1 cited
Histomorphometry of intra-acinar vessel muscularization in the rat sugen/hypoxia efficacy model of pulmonary arterial hypertension
Journal of Pharmacological and Toxicological Methods·2017· 1 cited
Soluble Fn14 Is Detected and Elevated in Mouse and Human Kidney Disease
PLoS ONE·2016· 30 citedOpen Access
Histomorphometry of Intra‐Acinar Vessel Muscularization in the Rat Sugen/Hypoxia Efficacy Model of Pulmonary Arterial Hypertension
The FASEB Journal·2016
Preclinical Safety Assessment of Drug Candidate‐Induced Pancreatic Toxicity
2016
Evaluation of Potential Safety Biomarkers for Monitoring Thrombogenic Potential of FXaI16L
Blood·2014· 3 cited
Mechanistic Investigations of Test Article–Induced Pancreatic Toxicity at the Endocrine–Exocrine Interface in the Rat
Toxicologic Pathology·2013· 24 cited
Loss of Coiled-Coil Domain Containing 80 Negatively Modulates Glucose Homeostasis in Diet-Induced Obese Mice
Endocrinology·2012· 22 cited
Safety and toxicological evaluation of a novel niacin-bound chromium (III) complex
Journal of Inorganic Biochemistry·2005· 62 cited
Respiratory tract toxicity of inhaled hydrogen sulfide in Fischer-344 rats, Sprague–Dawley rats, and B6C3F1 mice following subchronic (90-day) exposure
Toxicology and Applied Pharmacology·2004· 55 cited
OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OF INHALED MANGANESE PHOSPHATE TO THE RAT BRAIN
Journal of Toxicology and Environmental Health·2002· 171 cited
Olfactory Mucosal Necrosis in Male CD Rats Following Acute Inhalation Exposure to Hydrogen Sulfide: Reversibility and the Possible Role of Regional Metabolism
Toxicologic Pathology·2002· 49 cited
Nervous System
Elsevier eBooks·2002· 9 cited
Direct Olfactory Transport of Inhaled Manganese (54MnCl2) to the Rat Brain: Toxicokinetic Investigations in a Unilateral Nasal Occlusion Model
Toxicology and Applied Pharmacology·2000· 195 cited
Rudimentary Hemidesmosome Formation in Congenital Generalized Junctional Epidermolysis Bullosa in the Sprague-Dawley Rat
Veterinary Pathology·2000· 12 cited
Olfactory Neuron Loss in Adult Male CD Rats Following Subchronic Inhalation Exposure to Hydrogen Sulfide
Toxicologic Pathology·2000· 96 citedOpen Access
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Frequent Co-authors

David C. Dorman(9), Elizabeth A. Gross(4), Jameel Syed(4), R. Arden James(3), Shawn P. O’Neil(3), Yutian Zhan(3), Shashi K. Ramaiah(3), Brian A. Wong(2), Melanie F. Struve(2), Marianne W. Marshall(2), Laurence O. Whiteley(2), Michael F. McEntee(2), Sue Evans(2), Melissa Kennedy(2), Lauren M. Gauthier(2), Steven A. Bailey(2), Michael W. Bolt(2), Fei Hua(2), Steven Arkin(2), Kay A. Criswell(2)