Randy C. Eisensmith

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index2.8kcitations63works0.02yr avg
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Research Topics

Metabolism and Genetic Disorders(44), Folate and B Vitamins Research(22), Virus-based gene therapy research(16), Biochemical and Molecular Research(10), Mitochondrial Function and Pathology(8)

Publications63 total

Correction of the Genetic Defect in Alpha-1 Antitrypsin Deficiency by Somatic Gene Therapy
2020
IFN-γ sensitization of prostate cancer cells to fas-mediated death: a gene therapy approach
Molecular Therapy·2003· 30 citedOpen Access
A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus
Gene Therapy·2001· 114 cited
An Immunomodulatory Procedure That Stabilizes Transgene Expression and Permits Readministration of E1-Deleted Adenovirus Vectors
Molecular Therapy·2001· 23 citedOpen Access
Phenylketonuria
Encyclopedia of Genetics·2001
Stabilization of transgenes delivered by recombinant adenovirus vectors through extrachromosomal replication
The Journal of Gene Medicine·2000· 6 cited
Molecular Correlations in Phenylketonuria: Mutation Patterns and Corresponding Biochemical and Clinical Phenotypes in a Heterogeneous California Population
Pediatric Research·1999· 18 citedOpen Access
Pretreatment Serum Phenylalanine Levels As a Predictor of the Severity of the Mutation in the Phenylalanine Hydroxylase Gene and Phenylalanine Tolerance in Patients with Phenylketonuria
Journal of the American Dietetic Association·1999· 3 cited
Molecular genetics and outcome in PKU
Mental Retardation and Developmental Disabilities Research Reviews·1999
Molecular genetics and outcome in PKU
Mental Retardation and Developmental Disabilities Research Reviews·1999· 4 cited
Prospects for the treatment of phenylketonuria by gene therapy
Mental Retardation and Developmental Disabilities Research Reviews·1999· 3 cited
Hepatic Insulin Gene Expression as Treatment for Type 1 Diabetes Mellitus in Rats
Molecular Endocrinology·1997· 62 citedOpen Access
RFLP discordance in a PKU family due to a deletion in the PAH gene.
PubMed·1997· 12 cited
Viral Vector-Mediated Gene Therapy for Hemophilia B
Thrombosis and Haemostasis·1997· 15 cited
Correction of obesity and diabetes in genetically obese mice by leptin gene therapy
Proceedings of the National Academy of Sciences·1996· 159 cited
A Simple and Efficient Method for the Concentration and Purification of Recombinant Retrovirus for Increased Hepatocyte Transduction <i>In Vivo</i>
Human Gene Therapy·1996· 116 cited
Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer.
PubMed·1996· 143 cited
Somatic gene therapy for phenylketonuria and other hepatic deficiencies
Journal of Inherited Metabolic Disease·1996· 10 cited
Molecular basis of phenylketonuria and a correlation between genotype and phenotype in a heterogeneous southeastern US population.
PubMed·1996· 48 cited
Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs.
PubMed·1996· 108 cited
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Frequent Co-authors

Savio L.C. Woo(30), Alexei A. Goltsov(8), Y Okano(7), Wilson H.Y. Lo(6), Alexei I. Kuzmin(6), Yoshiyuki Okano(5), Tao Wang(5), Uta Lichter‐Konecki(4), David Konecki(4), M. Dasovich(4), S.L.C. Woo(4), Bingliang Fang(3), Elisabeth Svensson(3), Lars Hagenfeldt(3), Yi‐Tao Zeng(3), Lifang Yuan(3), Shen-Ru Liu(3), E.I. Schwartz(3), S Z Huang(3), Y T Zeng(3)