Johan Weigelt

Karolinska Institutet — Sweden

Medicine · Health Sciences

22h-index3.5kcitations44works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

PARP inhibition in cancer therapy(8), Protein Structure and Dynamics(6), Enzyme Structure and Function(6), DNA Repair Mechanisms(4), Computational Drug Discovery Methods(4)

Publications44 total

Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3
Journal of Medicinal Chemistry·2013· 13 citedOpen Access
PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3
ACS Chemical Biology·2013· 53 citedOpen Access
Improved Sensitivity in Label Free Technologies Provide New Possibilities for Structure Function Studies
Europe PMC (PubMed Central)·2013Open Access
Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening
Journal of Medicinal Chemistry·2012· 41 citedOpen Access
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
Nature Biotechnology·2012· 455 cited
A secretory system for bacterial production of high‐profile protein targets
Protein Science·2011· 48 citedOpen Access
Structural Basis for the Interaction between Tankyrase-2 and a Potent Wnt-Signaling Inhibitor
Journal of Medicinal Chemistry·2010· 117 citedOpen Access
A software tool to accelerate design of protein constructs for recombinant expression
Protein Expression and Purification·2010· 15 cited
Structural genomics—Impact on biomedicine and drug discovery
Experimental Cell Research·2010· 59 cited
Open-access public-private partnerships to enable drug discovery--new approaches.
PubMed·2010· 12 cited
Structure of the amino-terminal domain of human FK506-binding protein 3 / Northeast Structural Genomics Consortium Target HT99A
Biological Magnetic Resonance Bank·2010Open Access
The case for open‐access chemical biology
EMBO Reports·2009· 44 citedOpen Access
Structure determination of two potential parasitic drug targets of the SAHH family
Acta Crystallographica Section A Foundations of Crystallography·2009Open Access
Structural Basis for Inhibitor Specificity in Human Poly(ADP-ribose) Polymerase-3
Journal of Medicinal Chemistry·2009· 94 citedOpen Access
The DEXD/H-box RNA Helicase DDX19 Is Regulated by an α-Helical Switch
Journal of Biological Chemistry·2009· 134 citedOpen Access
Erratum to: ‘Structural genomics and drug discovery: all in the family’ [Curr Opin Chem Biol (2008) 12:32–39]
Current Opinion in Chemical Biology·2009· 4 cited
Zinc Binding Catalytic Domain of Human Tankyrase 1
Journal of Molecular Biology·2008· 62 citedOpen Access
Structural genomics and drug discovery: all in the family
Current Opinion in Chemical Biology·2008· 43 cited
Protein production and purification
Nature Methods·2008· 909 citedOpen Access
Solution NMR structure of the chromobox protein homolog 4
Biological Magnetic Resonance Bank·2008Open Access
page 1 of 3Next →

Frequent Co-authors

C.H. Arrowsmith(9), T. Karlberg(9), A.M. Edwards(8), Gottfried Otting(8), H. Schüler(7), M. Hammarstrom(6), A.G. Thorsell(5), Mats Wikström(5), M. Sundström(4), Natalia Markova(4), T. Ekblad(4), Johan Schultz(4), Caroline S. Miles(4), Nicholas E. Dixon(4), Christophe Farès(4), S. Gräslund(3), Linda Ball(3), R. Collins(3), L. Lehtiö(3), Anders E. G. Lindgren(3)