Nailya А. Zigangirova

Ministry of Health of the Russian Federation — Russia

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index186citations23works2.02yr avg
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Research Topics

Phenothiazines and Benzothiazines Synthesis and Activities(6), Antibiotic Resistance in Bacteria(5), SARS-CoV-2 and COVID-19 Research(4), Bacteriophages and microbial interactions(4), Antibiotics Pharmacokinetics and Efficacy(3)

Publications23 total

Oral Administration of the carboxylic acid ester prodrug NHC SN_9 protects mice from lethal Orthopoxvirus challenge: Implications for the Treatment of Monkeypox
2026Open Access
Single- and Multiple-dose Pharmacokinetics, Excretion, Metabolism, and Safety of the Antivirulence Agent Fluorothiazinone in Healthy Adults
Pharmaceutical Research·2025
The Small Molecule Inhibitor of the Type III Secretion System Fluorothiazinone Affects Flagellum Surface Presentation and Restricts Motility in Gram-Negative Bacteria
Antibiotics·2025· 1 citedOpen Access
<em>Escherichia coli</em> ST648 Chronically Infecting Patients with Cystic Fibrosis. An Approach to Eradication
Preprints.org·2025Open Access
A New “Non-Traditional” Antibacterial Drug Fluorothiazinone—Clinical Research in Patients with Complicated Urinary Tract Infections
Antibiotics·2024· 6 citedOpen Access
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
ACS Infectious Diseases·2024· 2 cited
New conjugates based on N4-hydroxycytidine with more potent antiviral efficacy in vitro than EIDD-2801 against SARS-CoV-2 and other human coronaviruses
Antiviral Research·2024· 3 citedOpen Access
Pharmacokinetics, tissue distribution, bioavailability and excretion of the anti-virulence drug Fluorothiazinon in rats and rabbits
The Journal of Antibiotics·2024· 4 cited
Synthesis and Antiviral Activity of Novel β-D-N4-Hydroxycytidine Ester Prodrugs as Potential Compounds for the Treatment of SARS-CoV-2 and Other Human Coronaviruses
Pharmaceuticals·2023· 1 citedOpen Access
Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators—Inhibitors of Bacterial Cystathionine γ-Lyase
International Journal of Molecular Sciences·2023· 8 citedOpen Access
Pharmacokinetics, quorum-sensing signal molecules and tryptophan-related metabolomics of the novel anti-virulence drug Fluorothiazinon in a Pseudomonas aeruginosa-induced pneumonia murine model
Journal of Pharmaceutical and Biomedical Analysis·2023· 8 cited
Identification of Key TRIM Genes Involved in Response to Pseudomonas aeruginosa or Chlamydia spp. Infections in Human Cell Lines and in Mouse Organs
International Journal of Molecular Sciences·2023· 6 citedOpen Access
Methylene Blue-Loaded NanoMOFs: Accumulation in <i>Chlamydia trachomatis</i> Inclusions and Light/Dark Antibacterial Effects
ACS Infectious Diseases·2023· 12 cited
NanoMOFs with Encapsulated Photosensitizer: Accumulation in <i>Chlamydia trachomatis</i> Inclusions and Antimicrobial Effects
2023· 1 citedOpen Access
Antiviral Activity of N1,N3-Disubstituted Uracil Derivatives against SARS-CoV-2 Variants of Concern
International Journal of Molecular Sciences·2022· 11 citedOpen Access
Preventative treatment with Fluorothiazinon suppressed Acinetobacter baumannii-associated septicemia in mice
The Journal of Antibiotics·2022· 21 citedOpen Access
Fluorothiazinon, a small-molecular inhibitor of T3SS, suppresses salmonella oral infection in mice
The Journal of Antibiotics·2021· 34 cited
Antibacterial agents reducing the risk of resistance development
Clinical Microbiology and Antimicrobial Chemotherapy·2021· 5 citedOpen Access
Lycopene presence in facial skin corneocytes and sebum and its association with circulating lycopene isomer profile: Effects of age and dietary supplementation
Food Science & Nutrition·2019· 6 citedOpen Access
A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones suppresses Salmonella infection in vivo
The Journal of Antibiotics·2016· 35 citedOpen Access
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Frequent Co-authors

Anna B. Sheremet(10), S. I. Luyksaar(8), Gintsburg Al(8), Анна Владимировна Соловьева(4), Vladimir А. Gushchin(4), Natalia E. Bondareva(4), Nadezhda L. Lubenec(4), Egor S. Zayakin(3), Ekaterina A. Koroleva(3), Elena Y. Morgunova(3), Elena Fedina(3), Andrei E. Siniavin(3), Sergey A. Zolotov(3), Denis Y. Logunov(3), Mark V. Savitskii(3), Alex Brito(3), Svetlana A. Appolonova(3), E.S. Darnotuk(3), Anna M. Inshakova(3), Svetlana A. Ermolaeva(3)