Eugene Bratoeff

Medicine · Health Sciences

20h-index1.2kcitations140works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Hormonal and reproductive studies(56), Estrogen and related hormone effects(46), Steroid Chemistry and Biochemistry(29), Prostate Cancer Treatment and Research(21), Crystallization and Solubility Studies(18)

Publications140 total

Pregnandiene-structures coupled with anti-inflammatory moieties as inhibitors of the 5[alpha]-reductase activity
Endocrine Abstracts·2022
Synthesis, <i>in silico</i>, and <i>in vivo</i> anti-inflammatory evaluation of 3β-cinnamoyloxy substituted pregna-4,16-diene-6,20-diones derivatives
Journal of Biomolecular Structure and Dynamics·2021· 1 cited
In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands
Current Enzyme Inhibition·2020
Effect of pregnenolone derivatives on the selective inhibition of 5α-reductase 2 activity
Endocrine Abstracts·2020
Effect of Pregnenolone Derivatives on the Selective Inhibition of 5α-Reductase 2 Activity
Current Enzyme Inhibition·2019· 2 cited
CCDC 932617: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1
Bioorganic & Medicinal Chemistry·2018· 3 citedOpen Access
17β-N-arylcarbamoylandrost-4-en-3-one Derivatives as Inhibitors of the Enzymes 3α-Hydroxysteroid Dehydrogenase and 5α-Reductase
Current Enzyme Inhibition·2018· 1 cited
Synthesis and cytotoxic effect of pregnenolone derivatives with one or two α,β-unsaturated carbonyls and an ester moiety at C-21 or C-3
Steroids·2018· 9 cited
Synthesis of new derivatives of 21-imidazolyl-16-dehydropregnenolone as inhibitors of 5α-reductase 2 and with cytotoxic activity in cancer cells
Bioorganic & Medicinal Chemistry·2017· 12 citedOpen Access
New Dehydroepiandrosterone-triazole Derivatives Identified as Inhibitors of 17β.-Hydroxysteroid Dehydrogenase Enzyme in the Prostate
Current Enzyme Inhibition·2016
Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line
European Journal of Medicinal Chemistry·2016· 12 cited
Synthesis and biological activity of two pregnane derivatives with a triazole or imidazole ring at C-21
The Journal of Steroid Biochemistry and Molecular Biology·2016· 17 cited
Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
Current Medicinal Chemistry·2016· 13 citedOpen Access
Activity landscape analysis of novel 5$$\upalpha $$-reductase inhibitors
Molecular Diversity·2016· 8 cited
Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1
Bioorganic & Medicinal Chemistry·2015· 13 citedOpen Access
Synthesis and biological evaluation of esters of 16-formyl-17-methoxy-dehydroepiandrosterone derivatives as inhibitors of 5α-reductase type 2
Journal of Enzyme Inhibition and Medicinal Chemistry·2015· 5 citedOpen Access
Novel dehydroepiandrosterone benzimidazolyl derivatives as 5<b>α</b>-reductase isozymes inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry·2015· 5 citedOpen Access
Synthesis and Identification of Pregnenolone Derivatives as Inhibitors of Isozymes of 5α‐Reductase
Archiv der Pharmazie·2015· 9 cited
Identification of the Effect of Novel Triazole-Dehydroepiandrosterone Derivatives as Inhibitors of 17β-Hydroxysteroid Dehydrogenase in Prostate
Current Enzyme Inhibition·2015
page 1 of 7Next →

Frequent Co-authors

Marisa Cabeza(40), Ivonne Heuze(19), Elena Ramı́rez(18), Yvonne Heuze(11), Mariana Garrido(9), Juan Soriano(8), Eugenio Flores(7), Sergio Recillas‐Morales(4), Araceli Sánchez(4), Aylin Viviana Silva Ortiz(4), Teresa Ramírez‐Ápan(4), Alfonso Romo de Vivar(3), Mauricio Sánchez(3), Alexandra Quiroz(3), Victor Haber Pérez(3), Tania Segura(3), Norma Valencia(3), Francisco Cortés‐Benítez(3), Alejandra Chávez‐Riveros(3), Victor Pérez-Ornelas(2)