J. Feeney

University of Guelph — Canada

Materials Science · Physical Sciences

52h-index9.2kcitations332works2.02yr avg
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Research Topics

Enzyme Structure and Function(78), Protein Structure and Dynamics(57), Molecular spectroscopy and chirality(44), Advanced NMR Techniques and Applications(43), Probiotics and Fermented Foods(31)

Publications332 total

Prenatal Intake of High Multivitamins or Folic Acid With or Without Choline Contributes to Gut Microbiota‐Associated Dysregulation of Serotonin in Offspring
Molecular Nutrition & Food Research·2025· 2 citedOpen Access
Magnetic Resonance, Historical Perspective
Elsevier eBooks·2016· 1 cited
L.casei DHFR-TRIMETHOPRIM complex
Biological Magnetic Resonance Bank·2012Open Access
NMR Structures of Apo <i>L. casei</i> Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions
Biochemistry·2011· 28 citedOpen Access
L.casei DHFR-NADPH complex
Open MIND·2011Open Access
Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers
2010
Life and Times of Eddy Zorro: A Review of the 2007 Gulf of Mexico Loop Current Activity
Proceedings of Offshore Technology Conference·2008
ChemInform Abstract: Forty Years of Progress in Nuclear Magnetic Resonance Spectroscopy
ChemInform·2008
1H and 15N chemical shifts of NH groups in DHFR complexes with brodimoprim analogues 3-5, methotrexate and trimethoprim.
Biological Magnetic Resonance Bank·2008Open Access
Structural factors determining the binding selectivity of the antibacterial drug trimethoprim to dihydrofolate reductase
Pharmaceutical Chemistry Journal·2007· 7 cited
Feeney, James: Personal Reminiscences on NMR
Encyclopedia of Magnetic Resonance·2007
Structural studies on Plasmodium vivax merozoite surface protein-1
Molecular and Biochemical Parasitology·2007· 47 cited
Forty years of Progress in Nuclear Magnetic Resonance Spectroscopy
Progress in Nuclear Magnetic Resonance Spectroscopy·2007· 47 cited
Solution structures and dynamics of the dihydrofolate reductase complexes with anti-bacterial drug trimethoprim
2007
Solution structure of L.casei dihydrofolate reductase complexed with NADPH, 32 structures
2006
1H, 15N and 13C resonance assignments of human dihydrofolate reductase in its complex with trimethoprim and NADPH
Biological Magnetic Resonance Bank·2006Open Access
Effects of Co-operative Ligand Binding on Protein Amide NH Hydrogen Exchange
Journal of Molecular Biology·2005· 30 cited
Solution Structure of Human Dihydrofolate Reductase in its Complex with Trimethoprim and NADPH
Journal of Biomolecular NMR·2005· 29 cited
NMR spectroscopy in drug research. Exploring the origins of cooperative effect of ligand binding to dihydrofolate reductase
2005
Interaction of calmodulin with the phosphofructokinase target sequence
FEBS Letters·2004· 18 citedOpen Access
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Frequent Co-authors

Gordon C. K. Roberts(17), B. Birdsall(16), A. S. V. Burgen(9), William D. Morgan(4), Mark D. Carr(4), Elizabeth F. Hounsell(4), Anthony A. Holder(3), N.J.M. Birdsall(3), P. Partington(3), Jean Pierre Albrand(3), Richard A. Williamson(3), T.A. Frenkiel(3), Robert B. Freedman(3), Ten Feizi(3), Barry J. Kimber(3), L. H. Sutcliffe(3), Stephen R. Martin(3), Christopher J. Bauer(3), D. Vaughan Griffiths(3), J. C. Metcalfe(2)