M Klemsz

University of British Columbia — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index3.8kcitations20works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(5), T-cell and B-cell Immunology(4), Genomics and Chromatin Dynamics(3), Sarcoma Diagnosis and Treatment(3), Immune Response and Inflammation(3)

Publications20 total

A Phase One, Open Label, Multi-Dose Study To Evaluate the Safety, Tolerability, and Biologic Effects of Three Doses of IW001 in Patients with Idiopathic Pulmonary Fibrosis (IPF)
The Journal of Heart and Lung Transplantation·2013· 3 citedOpen Access
53 PU.1 Expression Delineates Heterogeneity in Primary Th2 Cells
Pediatric Research·2006· 2 citedOpen Access
Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension
The Journal of Immunology·1997· 140 cited
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.
The EMBO Journal·1996· 1.1k citedOpen Access
Crystal structure of PU.1 ETS domain–DNA complex: a new pattern for helix-turn-helix recognition
Acta Crystallographica Section A Foundations of Crystallography·1996Open Access
PU.1 ETS DOMAIN-DNA COMPLEX
1996
The transcription factor PU.1 is involved in macrophage proliferation.
The Journal of Experimental Medicine·1996· 155 citedOpen Access
Hematopoietic Transcriptional Regulation by the Myeloid Zinc Finger Gene, MZF-1
Current topics in microbiology and immunology·1996· 89 cited
The ETS oncogene family in development, proliferation and neoplasia.
PubMed·1994· 55 cited
The Ewing’s Sarcoma <i>EWS/FLI-1</i> Fusion Gene Encodes a More Potent Transcriptional Activator and is a More Powerful Transforming Gene than <i>FLI-1</i>
Molecular and Cellular Biology·1993· 129 cited
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.
Molecular and Cellular Biology·1993· 498 citedOpen Access
Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1
Blood·1993· 210 citedOpen Access
Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells
Blood·1993· 1 citedOpen Access
Drosophila forkhead homologues are expressed in a lineage-restricted manner in human hematopoietic cells
Blood·1993· 31 citedOpen Access
Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation
Science·1993· 278 cited
Characterization of the ets oncogene family member, fli-1.
Journal of Biological Chemistry·1993· 87 citedOpen Access
Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11
Immunogenetics·1993· 4 cited
PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.
Molecular and Cellular Biology·1992· 356 citedOpen Access
The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.
Genes & Development·1990· 514 citedOpen Access
Induction of c-fos and c-myc expression during B cell activation by IL-4 and immunoglobulin binding ligands.
The Journal of Immunology·1989· 88 cited

Frequent Co-authors

Robert Hromas(9), Richard A. Maki(7), Scott R. McKercher(6), Jason H. Moore(4), R. Maki(3), Charles Van Beveren(3), Antonio Celada(2), Stephen L. Lessnick(2), Benjamin S. Braun(2), Lynn Lunsford(2), Christopher T. Denny(2), Sujatha Nagulapalli(2), Thomas Johnston(2), C Socha(2), R. Kodandapani(2), Frédéric Pio(2), C.‐Z. Ni(2), Gennaro Piccialli(2), Kathryn R. Ely(2), Bruce E. Torbett(1)