Hong Lei

Guangdong Pharmaceutical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index7.4kcitations46works0.52yr avg
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Research Topics

Epigenetics and DNA Methylation(12), Genetic Syndromes and Imprinting(8), Ubiquitin and proteasome pathways(5), Cancer-related gene regulation(5), Cancer, Hypoxia, and Metabolism(4)

Publications46 total

ZBTB7B inhibits glioma tumorigenicity by upregulating GPR17 and CXCL10
Journal of Molecular Cell Biology·2025Open Access
Methylomes of human CD4 and CD8 memory T lymphocytes reveal tissue-specific epigenetic signatures for maintenance and recall function
Immunity & Inflammation·2025Open Access
Coated sponge spicules for remodeling skin immune homeostasis in psoriasis treatment by releasing self-assembled phospholipid complex nanoparticles
Colloids and Surfaces B Biointerfaces·2025· 1 cited
Exploring Designer-Generative AI Collaborative Personas: A Case Study on ChatGPT
2024· 1 cited
Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression
eLife·2022· 20 citedOpen Access
Author response: Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression
2022Open Access
Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites
Nature Communications·2022· 31 citedOpen Access
Hypoxia Dynamically Regulates DBC1 Ubiquitination and Stability by SIAH2 and OTUD5 in Breast Cancer Progression
2022Open Access
PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer
Scientific Reports·2021· 5 citedOpen Access
PAX8 lineage-driven T cell-engaging antibody for the treatment of high-grade serous ovarian cancer
Research Square (Research Square)·2021· 1 citedOpen Access
LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy
Nature Cell Biology·2020· 73 citedOpen Access
Blue LED causes cell death in human hepatoma by inducing DNA damage
2020· 3 citedOpen Access
Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells
Journal of Biological Chemistry·2018· 19 citedOpen Access
Myocilin binding to a-b-crystallin sheds light on an old and blinding disease
2018
GW27-e1248 Blockage of HIF-1a/Notch1 signaling attenuates c-Kit+ bone marrow mesenchymal stem cells-contributed recovery of cardiac function following myocardial infarction
Journal of the American College of Cardiology·2016
Methods for PTEN in Stem Cells and Cancer Stem Cells
Methods in molecular biology·2015· 14 cited
ROS and MDA generation in Hepa 1–6 cells upon QD treatment.
Figshare·2015Open Access
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation
Journal of Molecular Medicine·2015· 95 cited
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation
Basic Research in Cardiology·2015· 77 cited
Chromodomain helicase DNA-binding 4 is required for proliferation, distal VH rearrangements and developmental progression of B cell progenitors (HEM1P.221)
The Journal of Immunology·2015
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Frequent Co-authors

En Li(9), En Li(7), Taiping Chen(5), Thomas B. Nicholson(5), Hui Su(4), Li‐Ling Wu(4), Kara Lukin(4), James Hagman(4), Sarah Hevi(3), Jeffrey Bajko(3), Brian Granda(3), Han Feng(3), Qiangqiang Liu(3), Jianyu Feng(3), Yanping Zhao(3), Biao Ma(3), Hongcheng Cheng(3), Chenglong Mu(3), Linbo Chen(3), Jiaojiao Zhang(3)