N M Bleehen

Medicine · Health Sciences

35h-index4.3kcitations130works0.02yr avg
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Research Topics

Glioma Diagnosis and Treatment(18), Cancer, Hypoxia, and Metabolism(14), Ultrasound and Hyperthermia Applications(13), Virus-based gene therapy research(11), Neuroendocrine Tumor Research Advances(11)

Publications130 total

A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy.
PubMed·2000· 188 cited
Phase I and pharmacokinetic study of DACA (XR5000): a novel inhibitor of topoisomerase I and II
British Journal of Cancer·1999· 28 citedOpen Access
O6-Methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma
British Journal of Cancer·1998· 86 citedOpen Access
A phase I study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma
European Journal of Cancer·1998· 54 cited
Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma
Cancer Chemotherapy and Pharmacology·1997· 219 cited
A short fractionation radiotherapy treatment for poor prognosis patients with high grade glioma
Clinical Oncology·1997· 45 cited
Nicotinamide and pentoxifylline increase human leucocyte filterability: a possible mechanism for reduction of acute hypoxia.
PubMed·1996· 6 cited
Phase I study of etoposide with SDZ PSC 833 as a modulator of multidrug resistance in patients with cancer.
Journal of Clinical Oncology·1996· 176 cited
Randomized trial of palliative two-fraction versus more intensive 13-fraction radiotherapy for patients with inoperable non-small cell lung cancer and good performance status
Clinical Oncology·1996· 232 cited
Phase II trials of rhizoxin in advanced ovarian, colorectal and renal cancer
British Journal of Cancer·1995· 14 citedOpen Access
A phase II study of oral piritrexim in recurrent high-grade (III, IV) glioma
British Journal of Cancer·1995· 11 cited
Insulin-like growth factor (IGF) and IGF binding proteins in growth hormone dysregulation and abnormal glucose tolerance in small cell lung cancer patients
European Journal of Cancer·1995· 1 cited
Response of 145 spontaneous canine head and neck tumours to radiation versus radiation plus microwave hyperthermia: Results of a randomized phase III clinical study
International Journal of Hyperthermia·1995· 11 cited
Can long-term survival be improved in patients with small-cell lung cancer (SCLC) and good performance status?
British Journal of Cancer·1994· 1 citedOpen Access
Role for membrane and secreted insulin-like growth factor-binding protein-2 in the regulation of insulin-like growth factor action in lung tumors
Lung Cancer·1994· 88 cited
[D-Arg1, D-Phe5, D-Trp7,9, Leu11] Substance-P Induces Apoptosis in Lung Cancer Cell Lines in Vitro
Biochemical and Biophysical Research Communications·1994· 47 cited
Paraffin wax‐embedded material as a source of DNA for the detection of somatic genetic changes
The Journal of Pathology·1993· 9 cited
Phase II study of carboplatin and adriamycin as second line chemotherapy in small cell lung cancer
Clinical Oncology·1993· 7 cited
Effects of Laminarin Sulphates on Transforming Growth Factor<sub>α</sub>and Basic Fibroblast Growth Factor
Planta Medica·1992· 1 cited
Production of neuromedin B and neuromedin B gene expression in human lung tumor cell lines
Lung Cancer·1992· 49 cited
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Frequent Co-authors

P R Twentyman(12), Paul Workman(10), J G Reeve(6), Pamela Rabbitts(4), Norma E. Fox(3), K A Wright(3), Chris Wiltshire(3), Davina J. Honess(3), J.T. Roberts(3), Michael I. Walton(3), M. Brada(2), MH Brampton(2), D.J. Boote(2), Ian F. Dennis(2), J Schwander(2), James Watson(2), Janet Watson(2), SP Stenning(2), D H Jones(2), James M. Ford(2)