J. McLeod Griffiss

Pinnacle Clinical Research — United States

Immunology and Microbiology · Life Sciences

45h-index6.5kcitations132works0.02yr avg
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Research Topics

Bacterial Infections and Vaccines(69), Pneumonia and Respiratory Infections(40), Glycosylation and Glycoproteins Research(22), Reproductive tract infections research(21), Escherichia coli research studies(13)

Publications132 total

Dosing Colistimethate Every 8 h Results in Higher Plasma Concentrations of Active Colistin Than Every 12-Hourly Dosing without Increase in Nephrotoxicity: A Phase 1 Pharmacokinetics Trial in Healthy Adult Volunteers
Antibiotics·2022· 6 citedOpen Access
The Chemistry and Biology of Lipooligosaccharides: The Endotoxins of Bacteria of the Respiratory and Genital Mucosae
2020· 5 cited
A randomized placebo-controlled pilot study of the effect and duration of Amphora, a multipurpose vaginal pH regulator, on vaginal pH
Clinical and Experimental Obstetrics & Gynecology·2019· 1 citedOpen Access
A two-part phase 1 study to establish and compare the safety and local tolerability of two nasal formulations of XF-73 for decolonisation of Staphylococcus aureus: A previously investigated 0.5 mg/g viscosified gel formulation versus a modified formulation
Journal of Global Antimicrobial Resistance·2019· 18 citedOpen Access
Development and validation of an LC-MS/MS method for the simultaneous determination of bedaquiline and rifabutin in human plasma
Journal of Pharmaceutical and Biomedical Analysis·2019· 18 cited
How to Identify Exposed Women Who Are Infected with Neisseria gonorrhoeae
Methods in molecular biology·2019· 4 cited
Effects of Rifamycin Coadministration on Bedaquiline Desmethylation in Healthy Adult Volunteers
Clinical Pharmacology in Drug Development·2018· 9 cited
1494. Vaginal pH: Associations with <i>Neisseria gonorrhoeae</i>, <i>Chlamydia trachomatis</i>, and <i>Trichomonas vaginalis</i>
Open Forum Infectious Diseases·2018Open Access
Post hoc analysis of a randomized placebo-controlled pilot study on the effect of Amphora®, an acid-buffering vaginal gel, on vaginal pH by baseline vaginal pH level
Fertility and Sterility·2018· 1 cited
Mycobactericidal activity of bedaquiline plus rifabutin or rifampin in ex vivo whole blood cultures of healthy volunteers: A randomized controlled trial
PLoS ONE·2018· 9 citedOpen Access
A Phase 1 Pharmacokinetic and Safety Study of Extended-Duration, High-dose Cefixime for Cephalosporin-resistant Neisseria gonorrhoeae in the Pharynx
Sexually Transmitted Diseases·2018· 21 citedOpen Access
Impact of Rifabutin or Rifampin on Bedaquiline Safety, Tolerability, and Pharmacokinetics Assessed in a Randomized Clinical Trial with Healthy Adult Volunteers
Antimicrobial Agents and Chemotherapy·2017· 32 citedOpen Access
Response
Clinical Trials·2016· 1 cited
A response adaptive randomization platform trial for efficient evaluation of Ebola virus treatments: A model for pandemic response
Clinical Trials·2016· 65 citedOpen Access
Phase 1 clinical trials of DAS181, an inhaled sialidase, in healthy adults
Antiviral Research·2015· 60 citedOpen Access
Safety and Pharmacokinetics of XOMA 3AB, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin A
Antimicrobial Agents and Chemotherapy·2014· 61 citedOpen Access
627 The Treatment and Revised Classification of Gallbladder Perforation in Acute Cholecystitis: The Importance of Intrahepatic and Abdominal Abscess Formation
Gastroenterology·2014· 1 citedOpen Access
Stability of Colistimethate Sodium in Aqueous Solution
Antimicrobial Agents and Chemotherapy·2012· 11 citedOpen Access
Lack of Lipid A Pyrophosphorylation and Functional <i>lptA</i> Reduces Inflammation by Neisseria Commensals
Infection and Immunity·2012· 54 citedOpen Access
The association between body mass index and severe biliary infections: a multivariate analysis
The American Journal of Surgery·2012· 6 cited
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Frequent Co-authors

Robert E. Mandrell(16), Michael A. Apicella(11), H. Schneider(10), Gary A. Jarvis(10), Bradford W. Gibson(5), R M Hamadeh(4), Peter A. Rice(4), Nancy J. Phillips(4), Uri Galili(3), Marlene Shero(3), Harry Smith(3), Ping‐Kun Zhou(3), Constance M. John(3), Michele Estabrook(3), B. L. Brandt(3), Ryohei Yamasaki(3), J J Kim(3), W D Zollinger(2), Patricia L. Altieri(2), Sanford Berman(2)