Saul J. Sharkis

Johns Hopkins University — United States

Medicine · Health Sciences

30h-index10.3kcitations97works0.02yr avg
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Research Topics

Hematopoietic Stem Cell Transplantation(22), Pluripotent Stem Cells Research(18), Mesenchymal stem cell research(16), Erythrocyte Function and Pathophysiology(11), Acute Myeloid Leukemia Research(10)

Publications97 total

Transient c-Src Suppression During Endodermal Commitment of Human Induced Pluripotent Stem Cells Results in Abnormal Profibrotic Cholangiocyte-Like Cells
Stem Cells·2018· 23 citedOpen Access
FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm
Cell stem cell·2012· 89 citedOpen Access
Abstract 995: Transient low doses of DNA demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
Cancer Research·2012
Pluripotent Stem Cell–Based Cancer Therapy: Promise and Challenges
Science Translational Medicine·2012· 66 cited
Transient Low Doses of DNA-Demethylating Agents Exert Durable Antitumor Effects on Hematological and Epithelial Tumor Cells
Cancer Cell·2012· 634 citedOpen Access
A clinically relevant population of leukemic CD34+CD38− cells in acute myeloid leukemia
Blood·2012· 216 citedOpen Access
The Clinical Relevance of Acute Myeloid Leukemia Stem Cells
Blood·2011· 3 cited
Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining
Mutation research. Fundamental and molecular mechanisms of mutagenesis·2011· 60 citedOpen Access
Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent stem cells
Blood·2011· 94 citedOpen Access
In Vivo Liver Regeneration Potential of Human Induced Pluripotent Stem Cells from Diverse Origins
Science Translational Medicine·2011· 250 citedOpen Access
Characterization of chronic myeloid leukemia stem cells
American Journal of Hematology·2010· 84 cited
Screening for self-renewal factors by a combination of mRNA and CGH microarray in human embryonic stem cells
Frontiers in Biology·2010
Generation of Human Induced Pluripotent Stem Cells from Liver Progenitor Cells by Only Small Molecules†
Hepatology·2010· 2 citedOpen Access
Hypoxia-Induced Mitogenic Factor (HIMF/FIZZ1/RELMα) Recruits Bone Marrow-Derived Cells to the Murine Pulmonary Vasculature
PLoS ONE·2010· 47 citedOpen Access
Abstract LB-88: Transient exposure to low-dose decitabine and azacytidine reprograms cancer cells to produce a prolonged antitumor response
Cancer Research·2010
Generation of Endoderm-Derived Human Induced Pluripotent Stem Cells From Primary Hepatocytes
Hepatology·2010· 255 citedOpen Access
Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma
Experimental Hematology·2009· 20 citedOpen Access
Isolation of Quiescent Murine Hematopoietic Stem Cells by Homing Properties
Methods in molecular biology·2008· 8 cited
Fetal to Adult Stem Cell Transition: Knocking Sox17 off
Cell·2007· 14 citedOpen Access
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
Blood·2007· 871 citedOpen Access
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Frequent Co-authors

Michael I. Collector(14), Yoon-Young Jang(12), Stephen B. Baylin(8), Richard J. Jones(6), Diane S. Krause(4), Curt I. Civin(4), Milada S. Vala(4), Jean‐Pierre J. Issa(3), Hua Liu(3), Zhaohui Ye(3), Yonghak Kim(3), Constance A. Griffin(3), Neil D. Theise(2), Sara Neutzel(2), Linzhao Cheng(2), D. Neil Watkins(2), James G. Herman(2), Carine Robert(2), Feyruz V. Rassool(2), William Matsui(2)