Tso-Pang Yao

Duke Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index10.0kcitations24works0.02yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(17), Ubiquitin and proteasome pathways(8), Epigenetics and DNA Methylation(5), Signaling Pathways in Disease(4), Autophagy in Disease and Therapy(3)

Publications24 total

Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production
Nature Communications·2014· 126 citedOpen Access
VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations
Neuron·2013· 236 citedOpen Access
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
The EMBO Journal·2011· 193 cited
HDACs in Skeletal Muscle Remodeling and Neuromuscular Disease
Handbook of experimental pharmacology·2011· 9 cited
HDAC6 controls autophagosome maturation essential for ubiquitin‐selective quality‐control autophagy
The EMBO Journal·2010· 734 citedOpen Access
Parathyroid Hormone-Related Peptide Represses Chondrocyte Hypertrophy through a Protein Phosphatase 2A/Histone Deacetylase 4/MEF2 Pathway
Molecular and Cellular Biology·2009· 142 citedOpen Access
The Neurodegenerative Disease Protein Ataxin-1 Antagonizes the Neuronal Survival Function of Myocyte Enhancer Factor-2
Journal of Biological Chemistry·2007· 50 citedOpen Access
HDAC6 Modulates Cell Motility by Altering the Acetylation Level of Cortactin
Molecular Cell·2007· 714 citedOpen Access
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Nature·2007· 1.2k cited
HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions
Journal of Cell Science·2007· 276 citedOpen Access
Intracellular Trafficking of Histone Deacetylase 4 Regulates Neuronal Cell Death
Journal of Neuroscience·2005· 186 citedOpen Access
Regulation of MEF2 by Histone Deacetylase 4- and SIRT1 Deacetylase-Mediated Lysine Modifications
Molecular and Cellular Biology·2005· 256 citedOpen Access
Regulation of the Dynamics of hsp90 Action on the Glucocorticoid Receptor by Acetylation/Deacetylation of the Chaperone
Journal of Biological Chemistry·2005· 162 citedOpen Access
The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase
Cancer Research·2005· 106 citedOpen Access
HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor
Molecular Cell·2005· 1.1k citedOpen Access
Cyclin D1 Inhibits Peroxisome Proliferator-activated Receptor γ-mediated Adipogenesis through Histone Deacetylase Recruitment
Journal of Biological Chemistry·2005· 272 citedOpen Access
AcK-knowledge Reversible Acetylation
Science s STKE·2004· 51 cited
Deactylase Inhibitors Disrupt Cellular Complexes Containing Protein Phosphatases and Deacetylases
Journal of Biological Chemistry·2004· 129 citedOpen Access
The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress
Cell·2003· 1.5k citedOpen Access
The Modular Nature of Histone Deacetylase HDAC4 Confers Phosphorylation-dependent Intracellular Trafficking
Journal of Biological Chemistry·2001· 156 citedOpen Access
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Frequent Co-authors

Timothy A. Bolger(4), Todd J. Cohen(4), Jeffrey J. Kovacs(3), J. Paul Taylor(3), Xuan Zhao(3), Yoshiharu Kawaguchi(2), Akihiro Ito(2), Udai Bhan Pandey(2), Gillian P. Ritson(2), Charlotte Hubbert(2), Patrick J. Murphy(2), William B. Pratt(2), Lian-Ee Ch'ng(2), Roderick T. Bronson(2), David M. Livingston(2), Joo‐Yong Lee(2), Emilie Tresse(2), Ronald M. Evans(2), Edward Seto(2), Adam C. McLaurin(1)