J.G.M. Klijn

Creighton University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index10.9kcitations150works0.02yr avg
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Research Topics

BRCA gene mutations in cancer(46), Estrogen and related hormone effects(32), HER2/EGFR in Cancer Research(23), Breast Cancer Treatment Studies(16), Growth Hormone and Insulin-like Growth Factors(16)

Publications150 total

Hormone Therapy and the Risk of Breast Cancer in BRCA1 Mutation Carriers
JNCI Journal of the National Cancer Institute·2008· 190 citedOpen Access
The use of genomic tools for the molecular understanding of breast cancer and to guide personalized medicine
Drug Discovery Today·2008· 17 cited
Response to first line chemotherapy in BRCA1 and BRCA2 mutation carriers with metastatic breast cancer (MBC)
European Journal of Cancer Supplements·2008
Who is prone to high levels of distress after prophylactic mastectomy and/or salpingo-ovariectomy?
Annals of Oncology·2007· 18 cited
Tumour characteristics, survival and prognostic factors of hereditary breast cancer from BRCA2-, BRCA1- and non-BRCA1/2 families as compared to sporadic breast cancer cases
European Journal of Cancer·2007· 234 cited
Passive coping and psychological distress in women adhering to regular breast cancer surveillance
Psycho-Oncology·2007· 50 cited
Family system characteristics and psychological adjustment to cancer susceptibility genetic testing: a prospective study
Clinical Genetics·2006· 74 cited
The course of distress in women at increased risk of breast and ovarian cancer due to an (identified) genetic susceptibility who opt for prophylactic mastectomy and/or salpingo-oophorectomy
European Journal of Cancer·2006· 63 cited
Tumor characteristics and detection method in the MRISC screening program for the early detection of hereditary breast cancer
Breast Cancer Research and Treatment·2006· 42 cited
Association between the CHEK2*1100delC germ line mutation and estrogen receptor status
International Journal of Gynecological Cancer·2006· 20 cited
Experience of parental cancer in childhood is a risk factor for psychological distress during genetic cancer susceptibility testing
Annals of Oncology·2006· 52 cited
Prognostic factors and impact of contralateral cancer on survival of hereditary breast cancer
European Journal of Cancer Supplements·2006
The psychological impact of regular surveillance in women at increased risk for hereditary breast cancer
European Journal of Cancer Supplements·2006· 2 cited
Age-specific tumour features, contralateral breast cancer (CBC) risk and survival in BRCA1-associated breast cancer
European Journal of Cancer Supplements·2006
Trends in endocrine therapy and chemotherapy for early breast cancer: a focus on the premenopausal patient
Journal of Cancer Research and Clinical Oncology·2006· 34 citedOpen Access
Survival and prognostic factors in BRCA1-associated breast cancer
Annals of Oncology·2005· 134 cited
[The value of gene expression profiles using micoarrays for the individualisation of adjuvant therapy after surgery for breast cancer].
PubMed·2005· 1 cited
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
The Lancet·2005· 1.2k cited
CYP2C19 genotype predicts duration of response to tamoxifen in advanced breast cancer
Clinical Pharmacology & Therapeutics·2005· 3 cited
Long-term follow-up of the Rotterdam study on prophylactic mastectomy versus surveillance in BRCA1/2 mutation carriers
Journal of Clinical Oncology·2004· 7 cited
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Frequent Co-authors

John A. Foekens(11), Caroline Seynaeve(10), Henk Portengen(8), Steven W. J. Lamberts(7), Aad Tibben(7), Wim L.J. van Putten(6), Cecile T.M. Brekelmans(6), C.C.M. Bartels(6), E.J. Meijers-Heijboer(6), Maxime P. Look(5), S.C. Henzen‐Logmans(5), L.C. Verhoog(5), Peter Devilee(5), E. Berns(5), H.J. Duivenvoorden(5), Madeleine M.A. Tilanus‐Linthorst(4), Albertus N. van Geel(4), J. Alexieva-Figusch(4), Martinus F. Niermeijer(4), Harry J. de Koning(4)