A F Suffredini

National Institutes of Health Clinical Center — United States

Immunology and Microbiology · Life Sciences

17h-index2.8kcitations25works0.02yr avg
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Research Topics

Immune Response and Inflammation(9), Sepsis Diagnosis and Treatment(5), Blood Coagulation and Thrombosis Mechanisms(3), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(3), Pneumocystis jirovecii pneumonia detection and treatment(3)

Publications25 total

Human Endotoxin Administration as an Experimental Model in Drug Development
Clinical Pharmacology & Therapeutics·2014· 51 citedOpen Access
Plasma dehydroepiandrosterone levels during experimental endotoxemia and anti-inflammatory therapy in humans
Critical Care Medicine·2000· 17 cited
Is the Dosing and Timing of the Intervention Adequate?
2000
Reply
The Journal of Infectious Diseases·1999Open Access
Circulating Leptin Levels during Acute Experimental Endotoxemia and Antiinflammatory Therapy in Humans
The Journal of Infectious Diseases·1998· 69 citedOpen Access
Recombinant tumor necrosis factor receptor p75 fusion protein (TNFR:Fc) alters endotoxin-induced activation of the kinin, fibrinolytic, and coagulation systems in normal humans.
PubMed·1998· 53 cited
Cofactors V and VIII after endotoxin administration to human volunteers
Thrombosis Research·1995· 16 cited
Effects of recombinant dimeric TNF receptor on human inflammatory responses following intravenous endotoxin administration
The Journal of Immunology·1995· 203 cited
202 THE NEUTROPHIL AS A THERAPEUTIC TARGET IN SEPTIC SHOCK
Shock·1995· 4 cited
200 SELECTED TREATMENT STRATEGIES FOR SEPTIC SHOCK BASED ON PROPOSED MECHANISMS OF PATHOGENESIS
Shock·1995· 2 cited
199 NITRIC OXIDE IN SEPSIS
Shock·1995· 2 cited
201 ANTICYTOKINE THERAPIES IN SEPTIC SHOCK
Shock·1995· 2 cited
Human polymorphonuclear leukocytes lack detectable nitric oxide synthase activity.
The Journal of Immunology·1994· 106 cited
Endotoxin administration to humans primes alveolar macrophages for increased production of inflammatory mediators
Journal of Clinical Immunology·1994· 57 cited
Neutrophil attractant protein-1 and monocyte chemoattractant protein-1 in human serum. Effects of intravenous lipopolysaccharide on free attractants, specific IgG autoantibodies and immune complexes.
The Journal of Immunology·1993· 74 cited
Compartmentalization of the acute cytokine response in humans after intravenous endotoxin administration
Journal of Applied Physiology·1993· 82 cited
Leukocyte CD18 monoclonal antibody worsens endotoxemia and cardiovascular injury in canines with septic shock
Journal of Applied Physiology·1993· 54 cited
Hyperphospholipasemia A2 in human volunteers challenged with intravenous endotoxin
Inflammation·1992· 37 cited
Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.
The Journal of Experimental Medicine·1991· 448 citedOpen Access
Ocular permeability after systemic administration of endotoxin in humans
Current Eye Research·1991· 6 cited
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Frequent Co-authors

Robert L. Danner(9), Charles Natanson(5), G. Daniel Martich(4), Joseph E. Parrillo(3), Frederick P. Ognibene(3), Henry Masur(3), Hugh L. Preas(3), George P. Chrousos(3), Joseph E. Parrillo(3), P. O. Eichacker(3), Debra Reda(2), Steven M. Banks(2), Margaret Tropea(2), Irwin M. Feuerstein(2), Joseph A. Kovacs(2), Arthur J. Boujoukos(2), Stefan R. Bornstein(2), Peter Q. Eichacker(2), Margaret M. Parker(1), Robert E. Cunnion(1)