James P. Marston

University of Sheffield — United Kingdom

Materials Science · Physical Sciences

5h-index218citations8works0.02yr avg
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Research Topics

Enzyme Structure and Function(4), Glycogen Storage Diseases and Myoclonus(4), Protein Kinase Regulation and GTPase Signaling(3), Cancer, Hypoxia, and Metabolism(3), Amino Acid Enzymes and Metabolism(3)

Publications8 total

Prioritization of Charge over Geometry in Transition State Analogues of a Dual Specificity Protein Kinase
Journal of the American Chemical Society·2011· 21 cited
Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis
Journal of the American Chemical Society·2010· 88 cited
The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP and 3phosphoglycerate
2009
Structural Tightening and Interdomain Communication in the Catalytic Cycle of Phosphoglycerate Kinase
Journal of Molecular Biology·2009· 7 cited
The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP, 3PG and magnesium trifluoride
2009
The catalytically active fully closed conformation of human phosphoglycerate kinase K219A mutant in complex with ADP, 3PG and aluminium trifluoride
2009
The Denatured State of N-PGK Is Compact and Predominantly Disordered
Journal of Molecular Biology·2008· 13 cited
Anionic Charge Is Prioritized over Geometry in Aluminum and Magnesium Fluoride Transition State Analogs of Phosphoryl Transfer Enzymes
Journal of the American Chemical Society·2008· 89 cited

Frequent Co-authors

Jonathan P. Waltho(8), Matthew J. Cliff(7), Nicola J. Baxter(6), G. Michael Blackburn(5), Andrea M. Hounslow(5), Matthew W. Bowler(4), Andrea Varga(4), J. Szabó(4), Mária Vas(4), A.M.H. Hownslow(2), Wolfgang Bermel(1), Nicholas H. Williams(1), Florian Hollfelder(1), David E. Wemmer(1), Xiaoxia Liu(1), Zhao Yufen(1), C. Jeremy Craven(1), Anthony R. Clarke(1), Michelle A.C. Reed(1), G. Michael Blackburn(1)