Michele L. Schaefer

Roswell Park Comprehensive Cancer Center — United States

Immunology and Microbiology · Life Sciences

28h-index3.5kcitations49works2.52yr avg
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Research Topics

Immunotherapy and Immune Responses(11), T-cell and B-cell Immunology(10), Olfactory and Sensory Function Studies(8), Anesthesia and Neurotoxicity Research(7), Intensive Care Unit Cognitive Disorders(6)

Publications49 total

Deciphering neutrophil dynamics in the focal lesion tumor microenvironment to overcome immunosuppression in multiple myeloma
Blood·2025· 5 citedOpen Access
Disruption of Extracellular Signal-Regulated Kinase Partially Mediates Neonatal Isoflurane Anesthesia-Induced Changes in Dendritic Spines and Cognitive Function in Juvenile Mice
International Journal of Molecular Sciences·2025Open Access
Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice via Canonical NO-mediated Protein Kinase-G Signaling
Anesthesiology·2022· 9 citedOpen Access
Neonatal Isoflurane Anesthesia or Disruption of Postsynaptic Density-95 Protein Interactions Change Dendritic Spine Densities and Cognitive Function in Juvenile Mice
Anesthesiology·2020· 26 citedOpen Access
Nitric Oxide Donor Prevents Neonatal Isoflurane-induced Impairments in Synaptic Plasticity and Memory
Anesthesiology·2018· 29 citedOpen Access
Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway
PLoS Biology·2017· 66 citedOpen Access
Sensitivity to isoflurane anesthesia increases in autism spectrum disorder Shank3+/∆c mutant mouse model
Neurotoxicology and Teratology·2016· 17 citedOpen Access
Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature
Journal of Neurosurgical Anesthesiology·2016· 36 citedOpen Access
Neuroinflammation in primary blast neurotrauma: Time course and prevention by torso shielding
Experimental Neurology·2016· 19 cited
Transgenic pigs with green fluorescent protein-labeled pancreatic beta cells
Diabetologia·2016
Manganese-Enhanced Magnetic Resonance Imaging as a Diagnostic and Dispositional Tool after Mild-Moderate Blast Traumatic Brain Injury
Journal of Neurotrauma·2015· 21 citedOpen Access
Using the Olfactory System as an <i>In Vivo</i> Model To Study Traumatic Brain Injury and Repair
Journal of Neurotrauma·2014· 14 cited
The Importance of Neurogenic Inflammation in Blast-Induced Neurotrauma
2013· 1 cited
Mouse Urinary Biomarkers Provide Signatures of Maturation, Diet, Stress Level, and Diurnal Rhythm
Chemical Senses·2010· 42 citedOpen Access
Application of classification methods when group sizes are unequal by incorporation of prior probabilities to three common approaches: Application to simulations and mouse urinary chemosignals
Chemometrics and Intelligent Laboratory Systems·2009· 10 cited
Variable Selection Using Iterative Reformulation of Training Set Models for Discrimination of Samples: Application to Gas Chromatography/Mass Spectrometry of Mouse Urinary Metabolites
Analytical Chemistry·2009· 33 citedOpen Access
Monte-Carlo methods for determining optimal number of significant variables. Application to mouse urinary profiles
Metabolomics·2009· 23 cited
Use of cluster separation indices and the influence of outliers: application of two new separation indices, the modified silhouette index and the overlap coefficient to simulated data and mouse urine metabolomic profiles
Journal of Chemometrics·2008· 28 cited
Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones
The Journal of Comparative Neurology·2005· 195 cited
Emerging views on the distinct but related roles of the main and accessory olfactory systems in responsiveness to chemosensory signals in mice
Hormones and Behavior·2004· 175 cited
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Frequent Co-authors

Jonathan Sprent(8), Louis J. Muglia(6), Diego Restrepo(6), Roger A. Johns(6), J J Mond(5), Maria Holmboe(5), Richard G. Brereton(5), Randall R. Reed(5), José Trevejo(5), Sherri K. Vogt(4), Christy Gray(4), Nina Heinrich(4), Thomas E. Finger(3), Robert Korngold(3), Lisa M. Muglia(3), C. David Mintz(3), Kanet Wongravee(3), Sarah J. Dixon(3), Fred D. Finkelman(3), Scott T. Wong(2)