Walker H. Busby

University of North Carolina at Chapel Hill — United States

Medicine · Health Sciences

43h-index5.4kcitations80works0.02yr avg
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Research Topics

Growth Hormone and Insulin-like Growth Factors(43), Metabolism, Diabetes, and Cancer(15), Cell Adhesion Molecules Research(12), Protease and Inhibitor Mechanisms(7), Pancreatic function and diabetes(7)

Publications80 total

Substitutions for Hydrophobic Amino Acids in the N-terminal Domains of IGFBP-3 and -5 Markedly Reduce IGF-I Binding and Alter Their Biologic Actions
UNC Libraries·2021· 12 citedOpen Access
Tissue Transglutaminase Facilitates the Polymerization of Insulin-like Growth Factor-binding Protein-1 (IGFBP-1) and Leads to Loss of IGFBP-1's Ability to Inhibit Insulin-like Growth Factor-I-stimulated Protein Synthesis
UNC Libraries·2021· 2 citedOpen Access
Identification of the Extracellular Matrix Binding Sites for Insulin-like Growth Factor-binding Protein 5
UNC Libraries·2021Open Access
Extracellular matrix contains insulin-like growth factor binding protein-5: potentiation of the effects of IGF-I
UNC Libraries·2021· 6 citedOpen Access
A Monoclonal Antibody Against  V 3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs
UNC Libraries·2021Open Access
Binding of Insulin-like Growth Factor (IGF)–Binding Protein-5 to Smooth-Muscle Cell Extracellular Matrix Is a Major Determinant of the Cellular Response to IGF-I
UNC Libraries·2021Open Access
Insulin-like Growth Factor-I-stimulated Insulin Receptor Substrate-1 Negatively Regulates Src Homology 2 Domain-containing Protein-tyrosine Phosphatase Substrate-1 Function in Vascular Smooth Muscle Cells
UNC Libraries·2020Open Access
Adiponectin Lowers Glucose Production by Increasing SOGA
UNC Libraries·2020Open Access
Oxidized LDL and Fructosamine Associated with Severity of Coronary Artery Atherosclerosis in Insulin Resistant Pigs Fed a High Fat/High NaCl Diet
UNC Libraries·2020Open Access
Modulation of integrin antagonist signaling by ligand binding of the heparin-binding domain of vitronectin to the αVβ3 integrin
UNC Libraries·2020Open Access
Role of the integrin αVβ3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress
UNC Libraries·2020Open Access
Identification of Compounds That Inhibit IGF-I Signaling in Hyperglycemia
UNC Libraries·2020Open Access
An anti-αVβ3 antibody inhibits coronary artery atherosclerosis in diabetic pigs
Atherosclerosis·2017· 10 cited
Oxidized LDL and Fructosamine Associated with Severity of Coronary Artery Atherosclerosis in Insulin Resistant Pigs Fed a High Fat/High NaCl Diet
PLoS ONE·2015· 9 citedOpen Access
Blocking Ligand Occupancy of the αVβ3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs
Endocrinology·2014· 50 citedOpen Access
Aldosterone Enhances IGF-I-Mediated Signaling and Biological Function in Vascular Smooth Muscle Cells
Endocrinology·2010· 31 citedOpen Access
Adiponectin Lowers Glucose Production by Increasing SOGA
American Journal Of Pathology·2010· 49 citedOpen Access
Insulin-like Growth Factor-I-stimulated Insulin Receptor Substrate-1 Negatively Regulates Src Homology 2 Domain-containing Protein-tyrosine Phosphatase Substrate-1 Function in Vascular Smooth Muscle Cells
Journal of Biological Chemistry·2010· 24 citedOpen Access
A Monoclonal Antibody Against α <sub>V</sub> β <sub>3</sub> Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs
Science Translational Medicine·2010· 41 citedOpen Access
Hyperglycemia Regulates the Sensitivity of Vascular Cells to IGF-I Stimulation
Research and perspectives in endocrine interactions·2009· 1 cited
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Frequent Co-authors

David R. Clemmons(36), Jane B. Clarke(7), Laura A. Maile(7), William W. Youngblood(5), John S. Kizer(5), Taek‐Jeong Nam(5), Robert H. McCusker(4), Gabriella Wright(4), D R Clemmons(4), Catherine Rees(3), John I. Jones(3), Christine E. Smith(3), Timothy C. Nichols(3), Kevin Sitko(3), Cecilia Camacho‐Hübner(2), David K. Snyder(2), David R. Clemmons(2), Jane H. Humm(2), Robert S. Bar(2), Mary Boes(2)