Craig Fairchild

Medicine · Health Sciences

14h-index2.2kcitations38works0.02yr avg
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Research Topics

Cancer Treatment and Pharmacology(25), Synthetic Organic Chemistry Methods(13), Microbial Natural Products and Biosynthesis(6), Microtubule and mitosis dynamics(5), HER2/EGFR in Cancer Research(5)

Publications38 total

Data from <i>IRS2</i> Copy Number Gain, <i>KRAS</i> and <i>BRAF</i> Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
2023Open Access
473. Qualification of a p24 ELISA Assay for Quantitation of Total Lentiviral Vector Concentration
Molecular Therapy·2016Open Access
Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport
Experimental Cell Research·2015· 6 cited
Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of <i>ASCL1</i> Gene Expression
Molecular Cancer Therapeutics·2015· 94 cited
<i>IRS2</i> Copy Number Gain, <i>KRAS</i> and <i>BRAF</i> Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines
Molecular Cancer Therapeutics·2014· 30 cited
Abstract 4125: Identification of candidate predictive biomarkers for the cdc7 kinase inhibitor BMS-863233/XL413
Cancer Research·2011
Abstract B195: Synergy between ixabepilone (Ixa) and trastuzumab (TZ): Investigation of the role of microtubule-associated protein (MAP-tau) and III tubulin (βIII) in HER2-positive (HER2+) breast cancer (BC)
Molecular Cancer Therapeutics·2009
Identification of Candidate Molecular Markers Predicting Sensitivity in Solid Tumors to Dasatinib: Rationale for Patient Selection
Cancer Research·2007· 337 citedOpen Access
Identification of pharmacogenomic markers for predicting sensitivity to BMS-354825, a SRC/ABL kinase inhibitor
Journal of Clinical Oncology·2005· 3 cited
Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays
Journal of Medicinal Chemistry·2004· 1.3k citedOpen Access
CCDC 191152: Experimental Crystal Structure Determination
The Cambridge Structural Database·2003Open Access
The Synthesis of Structurally Novel Bridged Glycosidic Fluoroindolocarbazoles as Topoisomerase I Inhibitors
Elsevier eBooks·2003
Preclinical antitumor activity of two novel taxanes
Cancer Chemotherapy and Pharmacology·2001· 47 cited
Synthesis and biological evaluation of C-1 and ring modified A-norpaclitaxels
Tetrahedron·1999· 9 cited
ChemInform Abstract: Structure—Activity Relationships Study at the 3′‐N Position of Paclitaxel. Part 1. Synthesis and Biological Evaluation of the 3′‐(t)‐Butylaminocarbonyloxy Bearing Paclitaxel Analogues.
ChemInform·1998
ChemInform Abstract: Studies in Sugar Chemistry. Part 7. Glucuronides of Podophyllum Derivatives
ChemInform·1998
Structure-activity relationships study at the 3′-N position of paclitaxel-part 1: Synthesis and biological evaluation of the 3′-(t)-butylaminocarbonyloxy bearing paclitaxel analogs
Bioorganic & Medicinal Chemistry Letters·1997· 7 cited
Synthesis and biological activity of A-nor-paclitaxel analogues
Bioorganic & Medicinal Chemistry·1997· 14 cited
Paclitaxel analogs modified in ring C: Synthesis and biological evaluation
Tetrahedron·1997· 23 cited
Diastereoselective addition of Grignard reagents to azetidine-2,3-dione: Synthesis of novel Taxol® analogues
Tetrahedron Letters·1996· 53 cited
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Frequent Co-authors

Vittorio Farina(15), Byron H. Long(12), Dolatrai M. Vyas(12), Kathy Johnston(10), John F. Kadow(10), Joydeep Kant(8), William C. Rose(8), Stephen W. Mamber(7), Shuhui Chen(5), David G. I. Kingston(5), S.‐H. CHEN(5), Karen A. Reeves(4), Tai W. Wong(4), Stella Huang(4), Jianmei Wei(4), Terrence W. Doyle(4), Joan M. Carboni(4), B H Long(4), Fei Huang(3), Bryon Long(3)