W. J. F. van der Vijgh

Medicine · Health Sciences

47h-index9.4kcitations197works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Chemotherapy-induced cardiotoxicity and mitigation(40), Chemotherapy-induced organ toxicity mitigation(34), Metal complexes synthesis and properties(32), Cancer Treatment and Pharmacology(32), Electron Spin Resonance Studies(25)

Publications196 total

Maligne aandoeningen
Bohn Stafleu van Loghum eBooks·2017
Toxicity of Antioxidants
Toxicology and Forensic Medicine - Open Journal·2016· 1 citedOpen Access
The contribution of the major metabolite 4′-O-methylmonoHER to the antioxidant activity of the flavonoid monoHER
Chemico-Biological Interactions·2015· 10 cited
Use of Human Ovarian Cancer Tumor Lines for Secondary Screening of New Platinum Compounds
2015
The flavonoid monoHER promotes the adaption to oxidative stress during the onset of NAFLD
Biochemical and Biophysical Research Communications·2014· 11 cited
The antioxidant flavonoid monoHER provides efficient protection and induces the innate Nrf2 mediated adaptation in endothelial cells subjected to oxidative stress
PharmaNutrition·2014· 22 cited
The flavonoid 7-mono-O-(β-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect
Toxicology in Vitro·2014· 24 cited
The antioxidant flavonoid monoHER effectively protects against oxidative stress in a cultured endothelial cell line at physiologically achievable concentrations
Free Radical Biology and Medicine·2012· 1 cited
An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoHER and quercetin
Free Radical Biology and Medicine·2011· 21 cited
Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
Drug Metabolism and Disposition·2011· 11 cited
An Essential Difference between the Flavonoids MonoHER and Quercetin in Their Interplay with the Endogenous Antioxidant Network
PLoS ONE·2010· 51 citedOpen Access
Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER
Free Radical Biology and Medicine·2009· 24 cited
The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study
British Journal of Cancer·2007· 62 citedOpen Access
Flavonoids as protectors against doxorubicin cardiotoxicity: Role of iron chelation, antioxidant activity and inhibition of carbonyl reductase
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2007· 131 citedOpen Access
Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials
Cardiovascular Toxicology·2007· 85 citedOpen Access
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice
British Journal of Cancer·2007· 42 citedOpen Access
Caspase-dependent and -independent suppression of apoptosis by monoHER in Doxorubicin treated cells
British Journal of Cancer·2007· 28 citedOpen Access
Long-term effects of 7-monohydroxyethylrutoside (monoHER) on DOX-induced cardiotoxicity in mice
Cancer Chemotherapy and Pharmacology·2006· 17 cited
Protectors against doxorubicin-induced cardiotoxicity: Flavonoids
Cell Biology and Toxicology·2006· 62 cited
The influence of the time interval between monoHER and doxorubicin administration on the protection against doxorubicin-induced cardiotoxicity in mice
Cancer Chemotherapy and Pharmacology·2006· 12 cited
page 1 of 10Next →

Frequent Co-authors

Aalt Bast(20), Herbert M. Pinedo(12), Guido R.M.M. Haenen(9), S.A.B.E. van Acker(7), Godefridus J. Peters(7), Paul Lips(5), J. C. Netelenbos(5), Dirk‐Jan van den Berg(4), F C van Ginkel(4), Jan B. Vermorken(4), Giuseppe Giaccone(4), I. Klein(4), F.A.A. van Acker(3), Bashir M. Rezk(3), Klaas Kramer(3), Joop A. Grimbergen(3), M. Treskes(3), Michèl N. J. L. Tromp(2), A Wiersinga(2), M. Jongen(2)