Haruhiro Okuda

National Institute of Health Sciences — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index3.8kcitations180works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(21), Glutathione Transferases and Polymorphisms(16), Free Radicals and Antioxidants(16), Pharmacogenetics and Drug Metabolism(15), Nanoparticle-Based Drug Delivery(13)

Publications180 total

A simple and rapid method to simultaneously analyze ciclesonide and its impurities in a ciclesonide metered-dose inhaler using on-line supercritical fluid extraction/supercritical fluid chromatography/quadrupole time-of-flight mass spectrometry
Journal of Pharmaceutical and Biomedical Analysis·2021· 4 citedOpen Access
Regulatory landscape of nanotechnology and nanoplastics from a global perspective
Regulatory Toxicology and Pharmacology·2021· 365 citedOpen Access
Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-μm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging
International Journal of Pharmaceutics·2021· 18 citedOpen Access
Temperature-Dependent Formation of <i>N</i>-Nitrosodimethylamine during the Storage of Ranitidine Reagent Powders and Tablets
Chemical and Pharmaceutical Bulletin·2020· 38 citedOpen Access
Education of Pharmaceutical Sciences and the Japanese Pharmacopoeia —Expectation to the Future—
YAKUGAKU ZASSHI·2020Open Access
Evaluation of off‐target effects of gapmer antisense oligonucleotides using human cells
Genes to Cells·2019· 76 citedOpen Access
Rapid and efficient high-performance liquid chromatography analysis of N-nitrosodimethylamine impurity in valsartan drug substance and its products
Scientific Reports·2019· 61 citedOpen Access
Analysis of an Impurity, <i>N</i>-Nitrosodimethylamine, in Valsartan Drug Substances and Associated Products Using GC-MS
Biological and Pharmaceutical Bulletin·2019· 32 citedOpen Access
Detailed Morphological Characterization of Nanocrystalline Active Ingredients in Solid Oral Dosage Forms Using Atomic Force Microscopy
AAPS PharmSciTech·2019· 1 cited
Emerging technologies for food and drug safety
Regulatory Toxicology and Pharmacology·2018· 25 citedOpen Access
Evaluating the Properties of Poly(lactic-<i>co</i>-glycolic acid) Nanoparticle Formulations Encapsulating a Hydrophobic Drug by Using the Quality by Design Approach
Chemical and Pharmaceutical Bulletin·2017· 9 citedOpen Access
デザインアプローチによる品質を用いる疎水性薬物を封入したポリ(乳酸‐co‐グリコール酸)ナノ粒子製剤の特性の評価
Chemical and Pharmaceutical Bulletin·2017Open Access
Identification of Pseudopolymorphism of Magnesium Stearate by Using Low-Frequency Raman Spectroscopy
Organic Process Research & Development·2016· 18 cited
Scientific and regulatory approaches to confirm quality and improve patient perceptions of generic drug products in Japan
AAPS Open·2016· 11 citedOpen Access
Atomic Force Microscopic Analysis of the Effect of Lipid Composition on Liposome Membrane Rigidity
Langmuir·2016· 134 cited
Observation of liposomes of differing lipid composition in aqueous medium by means of atomic force microscopy
Microscopy·2016· 21 cited
An outline of chemotherapeutic response analysis in irinotecan-treated cancer patients using a combined method consisting of a knowledge-based algorithm for identifying SNPs (KB-SNP), 2 stages of screening, and the permutation test.
Figshare·2015Open Access
Irinotecan-treated cancer patients with SNP information, genetic factor, and clinical parameters for incidence of diarrhea.
Figshare·2015Open Access
Comparison of AIC, AUC, and ROC curves for logistic regression models.
Figshare·2015· 1 citedOpen Access
Interaction kinetics of serum proteins with liposomes and their effect on phospholipase-induced liposomal drug release
International Journal of Pharmaceutics·2015· 20 cited
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Frequent Co-authors

Masaaki Kurihara(13), Yosuke Demizu(11), Kiyoshi Fukuhara(11), Tadashi Watabe(8), Yukihiro Goda(8), Ikuo Nakanishi(8), Toshihiko Ozawa(8), Nobuo Ikota(8), Naoki Miyata(7), Kenichiro Ogura(6), Kumiko Sakai‐Kato(6), Toru Kawanishi(6), Kei Ohkubo(6), Shunichi Fukuzumi(6), Shiro Urano(6), Mitsunobu Doi(6), Masakazu Tanaka(6), Wataru Hakamata(5), Ken‐ichi Izutsu(5), Yukiko Sato(5)