F. James Primus

University of California, San Francisco — United States

Medicine · Health Sciences

37h-index4.5kcitations89works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(40), Radiopharmaceutical Chemistry and Applications(39), Immunotherapy and Immune Responses(23), Glycosylation and Glycoproteins Research(13), CAR-T cell therapy research(8)

Publications89 total

Apolipoprotein E deficiency improves survival in sepsis
Journal of the American College of Surgeons·2012· 1 cited
BMP-14 Gene Therapy Increases Tendon Tensile Strength in a Rat Model of Achilles Tendon Injury
Journal of Bone and Joint Surgery·2007· 137 cited
BMP-14 Gene Therapy Increases Tendon Tensile Strength in a Rat Model of Achilles Tendon Injury
Journal of Bone and Joint Surgery·2007· 81 cited
Adenovirus Fiber Shaft Contains a Trimerization Element That Supports Peptide Fusion for Targeted Gene Delivery
Journal of Virology·2006· 17 citedOpen Access
Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)‐expressing colon cancer using genetically modified dendritic cells that express CEA and T helper‐type 1 cytokines in CEA transgenic mice
International Journal of Cancer·2006· 54 citedOpen Access
Argon Beam Coagulation as an Adjuvant for Local Control of Giant Cell Tumor
Clinical Orthopaedics and Related Research·2006· 103 cited
CpG oligonucleotides enhance the tumor antigen-specific immune response of an anti-idiotype antibody-based vaccine strategy in CEA transgenic mice
Cancer Immunology Immunotherapy·2005· 26 citedOpen Access
DNA-based vaccines activate innate and adaptive antitumor immunity by engaging the NKG2D receptor
Proceedings of the National Academy of Sciences·2005· 47 citedOpen Access
Rationale for Antiangiogenic Cancer Therapy with Vaccination Using Epitope Peptides Derived from Human Vascular Endothelial Growth Factor Receptor 2
Cancer Research·2005· 101 cited
Dendritic Cells Pulsed with an Anti-Idiotype Antibody Mimicking Carcinoembryonic Antigen (CEA) Can Reverse Immunological Tolerance to CEA and Induce Antitumor Immunity in CEA Transgenic Mice
Cancer Research·2004· 39 cited
A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen–based DNA minigene vaccines
Journal of Clinical Investigation·2004· 28 citedOpen Access
A novel transgenic mouse model for immunological evaluation of carcinoembryonic antigen–based DNA minigene vaccines
Journal of Clinical Investigation·2004· 32 citedOpen Access
In vivo targeting of an anti-tumor antibody coupled to antigenic MHC class I complexes induces specific growth inhibition and regression of established syngeneic tumor grafts.
PubMed·2003· 18 cited
Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity.
PubMed·2003· 23 cited
Immunocytokines: Versatile Molecules for Biotherapy of Malignant Disease
2002
An oral DNA vaccine against human carcinoembryonic antigen (CEA) prevents growth and dissemination of Lewis lung carcinoma in CEA transgenic mice
Vaccine·2001· 56 cited
A Dual-Function DNA Vaccine Encoding Carcinoembryonic Antigen and CD40 Ligand Trimer Induces T Cell-Mediated Protective Immunity Against Colon Cancer in Carcinoembryonic Antigen-Transgenic Mice
The Journal of Immunology·2001· 106 citedOpen Access
Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.
PubMed·2001· 50 cited
Targeting and therapy of carcinoembryonic antigen-expressing tumors in transgenic mice with an antibody-interleukin 2 fusion protein.
PubMed·2000· 76 cited
Induction of cytotoxic T cells and their antitumor activity in mice transgenic for carcinoembryonic antigen
Cancer Immunology Immunotherapy·2000· 39 citedOpen Access
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Frequent Co-authors

David M. Goldenberg(17), Robert M. Sharkey(9), D M Goldenberg(7), Ralph A. Reisfeld(6), Rong Xiang(5), Frank H. DeLand(4), Sidney Bennett(4), Jean F. Simpson(4), M. Frederick Hawthorne(4), John R. van Nagell(3), K J Rickard-Dickson(3), J M Ruehlmann(3), Andreas G. Niethammer(3), Carrie S. Dolman(3), Stephen D. Gillies(3), G. Szalai(3), Lawrence E. Williams(3), Hans J. Hansen(3), He Zhou(3), Yunping Luo(3)