Régine Losson

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index8.5kcitations90works0.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(23), Retinoids in leukemia and cellular processes(18), Estrogen and related hormone effects(17), Fungal and yeast genetics research(11), Protein Degradation and Inhibitors(11)

Publications90 total

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia
Nature Communications·2020· 26 citedOpen Access
PF449 INACTIVATION OF THE NUCLEAR INTERACTING SET DOMAIN PROTEIN 1 IMPAIRS GATA1‐REGULATED TERMINAL ERYTHROID MATURATION AND INDUCES ERYTHROLEUKEMIA
HemaSphere·2019Open Access
TRIM28 is essential for erythroblast differentiation in the mouse
Blood·2013· 33 citedOpen Access
Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA
Nature Structural & Molecular Biology·2013· 74 cited
Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition
Development·2012· 26 citedOpen Access
Tif1γ Suppresses Murine Pancreatic Tumoral Transformation by a Smad4-Independent Pathway
American Journal Of Pathology·2012· 33 citedOpen Access
TRIM Involvement in Transcriptional Regulation
Advances in experimental medicine and biology·2012· 23 cited
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
The Journal of Cell Biology·2011· 1 cited
Tripartite Motif 24 (Trim24/Tif1α) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor α (Rarα) Inhibition
Journal of Biological Chemistry·2011· 77 citedOpen Access
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
The Journal of Experimental Medicine·2011· 109 citedOpen Access
Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia
Journal of Clinical Investigation·2011· 108 citedOpen Access
51 Transcription Intermediary Factor 1 gamma (TIF1γ) is an epigenetically-regulated tumor suppressor gene in human chronic myelomonocytic leukemia
Leukemia Research·2011
L3MBTL2 Protein Acts in Concert with PcG Protein-Mediated Monoubiquitination of H2A to Establish a Repressive Chromatin Structure
Molecular Cell·2011· 139 citedOpen Access
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
Proceedings of the National Academy of Sciences·2011· 213 cited
Adult Hematopoiesis is Regulated by TIF1γ, a Repressor of TAL1 and PU.1 Transcriptional Activity
Cell stem cell·2011· 42 citedOpen Access
TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis
Developmental Biology·2010· 25 cited
Negative control of Smad activity by ectodermin/Tif1γ patterns the mammalian embryo
Development·2010· 85 citedOpen Access
Nizp1 zinc finger protein localization is determined by SCAN-domain inclusion regulated through alternative splicing
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2010· 2 cited
The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2010· 16 cited
Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma
Proceedings of the National Academy of Sciences·2009· 206 citedOpen Access
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Frequent Co-authors

Pierre Chambon(23), Florence Cammas(11), David M. Heery(6), Konstantin Khetchoumian(6), Benoı̂t Pierrat(6), Bertrand Le Douarin(5), Hinrich Gronemeyer(5), Pierre Chambon(5), Thierry Lerouge(5), Anders Lade Nielsen(4), Mustapha Oulad‐Abdelghani(4), J A Ortíz(4), Manuel Mark(4), Kai-Ping Yan(4), F. Lacroute(3), Benjamin Herquel(3), Marius Teletin(3), Daniel Metzger(3), Christina Zechel(2), Yves Lutz(2)