George C. Ruben

Dartmouth College — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

26h-index2.5kcitations93works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(15), Bacteriophages and microbial interactions(13), Mesoporous Materials and Catalysis(11), Alzheimer's disease research and treatments(8), Advanced Electron Microscopy Techniques and Applications(8)

Publications93 total

Microscopy research and technique (MRT)
Microscopy Research and Technique·2006
Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: Negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation
Microscopy Research and Technique·2005· 26 cited
Alzheimer paired helical filaments (PHFs) studied by high‐resolution TEM: What can vertical Pt‐C replication tell us about the organization of the pronase‐digested PHF core?
Microscopy Research and Technique·2005· 4 cited
Commentary
Journal of Alzheimer s Disease·2001· 1 cited
The Iso-Competition Point, a New Concept for Characterizing Multivalent versus Monovalent Counterion Competition, Successfully Describes Cation Binding to DNA
Biophysical Journal·1999· 8 citedOpen Access
Vertical Pt–C Replication for TEM, A Revolution in Imaging Non-Periodic Macromolecules, Biological Gels and Low-Density Polymer Networks
Micron·1998· 10 citedOpen Access
DNA bound to polypyrrole films: high-resolution imaging, DNA binding kinetics and internal migration
Biomaterials·1998· 20 citedOpen Access
Cell-Free DNA in Human Blood Plasma
Pancreas·1998· 379 cited
Alzheimer disease hyperphosphorylated tau aggregates hydrophobically
Synapse·1997· 25 citedOpen Access
Alzheimer disease hyperphosphorylated tau aggregates hydrophobically
Synapse·1997
Conformation ofLac repressor tetramer in solution, bound and unbound to operator DNA
Microscopy Research and Technique·1997· 36 cited
Conformation of Lac repressor tetramer in solution, bound and unbound to operator DNA
Microscopy Research and Technique·1997· 1 cited
518 Secondary structure of Alzheimer disease abnormally hyperphosphorylated tau (AD P-Tau) before and after phosphate removal using hydroflouric acid: Correlation with high resolution TEM imaging
Neurobiology of Aging·1996
Quantification of particle sizes with metal replication under standard freeze‐etching conditions: A gold ball standard for calibrating shadow widths was used to measure freeze‐etched globular proteins
Microscopy Research and Technique·1995· 4 cited
High resolution transmission electron microscopy nanostructure of condensed-silica aerogels
Journal of Non-Crystalline Solids·1995· 34 citedOpen Access
High-resolution transmission electron microscopy of the nanostructure of melamine-formaldehyde aerogels
Journal of Non-Crystalline Solids·1995· 47 citedOpen Access
Alzheimer paired helical filaments, untreated and pronase digested, studied by vertical platinum-carbon replication and high resolution transmission electron microscopy
Brain Research·1995· 20 citedOpen Access
High resolution platinum‐carbon replication of freeze‐dried basement membrane
Microscopy Research and Technique·1994· 37 cited
Secondary structure of proteins associated in thin films
Biopolymers·1993· 55 cited
The organization of the microtubule associated protein tau in Alzheimer paired helical filaments
Proceedings annual meeting Electron Microscopy Society of America·1993
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Frequent Co-authors

Kenneth A. Marx(11), Khalid Iqbal(7), Peter D. Yurchenco(5), Inge Grundke‐Iqbal(5), M. W. Shafer(3), H. M. Wiśniewski(3), John E. Johnson(3), Thomas B. Roos(2), Thomas L. Ciardelli(2), R.W. Pekala(2), Thomas M. Tillotson(2), L.W. Hrubesh(2), Benjamin M. Siegel(2), Ernest Jay(2), Paul Spielman(2), Chen‐Pei D. Tu(2), John N. Telford(2), Gordon H. Bokelman(2), William Krakow(2), Thomas C. Reynolds(2)