Jeffrey M. Harmon

Uniformed Services University of the Health Sciences — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index2.3kcitations37works0.02yr avg
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Research Topics

Estrogen and related hormone effects(12), Endoplasmic Reticulum Stress and Disease(7), Receptor Mechanisms and Signaling(6), Sphingolipid Metabolism and Signaling(5), Monoclonal and Polyclonal Antibodies Research(4)

Publications37 total

The ORMs interact with transmembrane domain 1 of Lcb1 and regulate serine palmitoyltransferase oligomerization, activity and localization
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2018· 40 cited
Expression of the ORMDLS, Modulators of Serine Palmitoyltransferase, Is Regulated by Sphingolipids in Mammalian Cells
Journal of Biological Chemistry·2014· 46 citedOpen Access
Autophagy regulates sphingolipid levels in the liver
Journal of Lipid Research·2014· 48 citedOpen Access
Topological and Functional Characterization of the ssSPTs, Small Activating Subunits of Serine Palmitoyltransferase
Journal of Biological Chemistry·2013· 64 citedOpen Access
The Pyridoxal 5′-Phosphate (PLP)-Dependent Enzyme Serine Palmitoyltransferase (SPT): Effects of the Small Subunits and Insights from Bacterial Mimics of Human hLCB2a HSAN1 Mutations
BioMed Research International·2013· 10 citedOpen Access
New subunits of SPT: New insights into LCB diversity and human disease
The FASEB Journal·2011
Sphingolipids in the Root Play an Important Role in Regulating the Leaf Ionome in<i>Arabidopsis thaliana</i>   
The Plant Cell·2011· 132 citedOpen Access
A Disease-causing Mutation in the Active Site of Serine Palmitoyltransferase Causes Catalytic Promiscuity
Journal of Biological Chemistry·2010· 100 citedOpen Access
Overexpression of the Wild-Type SPT1 Subunit Lowers Desoxysphingolipid Levels and Rescues the Phenotype of HSAN1
Journal of Neuroscience·2009· 98 citedOpen Access
Identification of small subunits of mammalian serine palmitoyltransferase that confer distinct acyl-CoA substrate specificities
Proceedings of the National Academy of Sciences·2009· 266 citedOpen Access
Tsc10p and FVT1: topologically distinct short-chain reductases required for long-chain base synthesis in yeast and mammals
Journal of Lipid Research·2009· 27 citedOpen Access
Expression of a Novel Marine Viral Single-chain Serine Palmitoyltransferase and Construction of Yeast and Mammalian Single-chain Chimera
Journal of Biological Chemistry·2006· 58 citedOpen Access
The Topology of the Lcb1p Subunit of Yeast Serine Palmitoyltransferase
Journal of Biological Chemistry·2004· 65 citedOpen Access
Glucocorticoid Receptor, Natural Mutations of
Encyclopedia of Hormones·2003
Role of serine phosphorylation of Stat5a in prolactin-stimulated β-casein gene expression
Molecular and Cellular Endocrinology·2001· 79 cited
Glucocorticoid-induced cell death requires autoinduction of glucocorticoid receptor expression in human leukemic T cells.
PubMed·1999· 106 cited
Glucocorticoid-Induced Apoptosis and Regulation of NF-κB Activity in Human Leukemic T Cells*
Endocrinology·1998· 73 citedOpen Access
Hormone-Independent Repression of AP-1-Inducible Collagenase Promoter Activity by Glucocorticoid Receptors
Molecular and Cellular Biology·1995· 59 citedOpen Access
Glucocorticoid receptor binding to rat liver nuclei occurs without nuclear transport
The Journal of Steroid Biochemistry and Molecular Biology·1993· 6 cited
Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90
Biochemistry·1993· 128 cited
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Frequent Co-authors

Teresa Dunn(13), E. Brad Thompson(11), Sita D. Gupta(11), Gongshe Han(9), Kenneth Gable(9), Niranjanakumari Somashekarappa(5), Thomas J. Schmidt(5), Laura P. Eisen(4), S. Stoney Simons(3), Dagmar Bačíková(3), Lisa A. Urda(3), Richard L. Proia(3), M S Elsasser(3), Prasun Moitra(2), Florian Eichler(2), Robert H. Brown(2), M. R. Norman(2), Jyoti Ramdas(2), Ken Gable(2), Lianying Yan(2)