Ewald Schröder

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index5.0kcitations30works4.02yr avg
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Research Topics

Redox biology and oxidative stress(16), Nitric Oxide and Endothelin Effects(4), Heat shock proteins research(4), Sulfur Compounds in Biology(4), Cellular Mechanics and Interactions(3)

Publications30 total

SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2
EMBO Molecular Medicine·2025· 2 citedOpen Access
Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
Cancer Cell·2024· 6 citedOpen Access
Sulforaphane-mediated inhibition of SHP2 as a potential pharmacotherapy for Noonan syndrome
Free Radical Biology and Medicine·2018
The oxygenating constituent of 3,6-diketocamphane monooxygenase from the CAM plasmid of<i>Pseudomonas putida</i>: the first crystal structure of a type II Baeyer–Villiger monooxygenase. Corrigendum
Acta Crystallographica Section D Structural Biology·2018· 4 citedOpen Access
Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2
Journal of Biological Chemistry·2016· 48 citedOpen Access
<i>S</i> ‐glutathiolation impairs phosphoregulation and function of cardiac myosin‐binding protein C in human heart failure
The FASEB Journal·2016· 35 citedOpen Access
The oxygenating constituent of 3,6-diketocamphane monooxygenase from the CAM plasmid of<i>Pseudomonas putida</i>: the first crystal structure of a type II Baeyer–Villiger monooxygenase
Acta Crystallographica Section D Biological Crystallography·2015· 23 citedOpen Access
Detection of Systemic Modification of Proteins in Mice by Sulforaphane after Oral Consumption
Free Radical Biology and Medicine·2012
Characterization of Redox Changes in Cardiac DJ-1 during Oxidant Stress
Free Radical Biology and Medicine·2012
Co-Crystal Structures of Inhibitors with MRCKβ, a Key Regulator of Tumor Cell Invasion
PLoS ONE·2011· 49 citedOpen Access
Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth
Cancer Cell·2011· 530 citedOpen Access
Glyceraldehyde 3-Phosphate Dehydrogenase is Unlikely to Mediate Hydrogen Peroxide Signaling: Studies with a Novel Anti-Dimedone Sulfenic Acid Antibody
Antioxidants and Redox Signaling·2010· 90 cited
Hydrogen Peroxide and Cysteine Protein Signaling Pathways
2009· 5 cited
Cardiac peroxiredoxins undergo complex modifications during cardiac oxidant stress
American Journal of Physiology-Heart and Circulatory Physiology·2008· 51 citedOpen Access
Abstract 151: H2O2 Operates As An Endothelium-derived Hyperpolarizing Factor By Directly Activating Protein Kinase G (PKG) I{alpha} Independently Of cGMP Via Disulfide Formation
Circulation·2007
Cysteine Redox Sensor in PKGIa Enables Oxidant-Induced Activation
Science·2007· 454 cited
Protein Sulfenation as a Redox Sensor
Molecular & Cellular Proteomics·2007· 183 citedOpen Access
Direct activation of Type I protein kinase a (PKA) by oxidants independently of cAMP is mediated by RI subunit interprotein disulphide bond formation
Circulation·2006· 28 cited
Formation, TEM study and 3D reconstruction of the human erythrocyte peroxiredoxin-2 dodecahedral higher-order assembly
Micron·2006· 60 cited
Oxidant-induced Activation of Type I Protein Kinase A Is Mediated by RI Subunit Interprotein Disulfide Bond Formation
Journal of Biological Chemistry·2006· 240 citedOpen Access
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Frequent Co-authors

Philip Eaton(15), Joseph R. Burgoyne(8), Jonathan P. Brennan(6), Rebecca L. Charles(5), Michail N. Isupov(5), Jennifer A. Littlechild(4), J. Robin Harris(3), Leslie B. Poole(3), Michael F. Olson(3), Friederike Cuello(3), Sonya C. Bardswell(3), William Fuller(3), Robin Wait(3), Shajna Begum(3), Jonathan C. Kentish(3), Mariana Fernández-Caggiano(3), Manuel Mayr(3), Oleksandra Prysyazhna(3), Michael S. Samuel(2), José I. López(2)