Christian Beaudry

Translational Genomics Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.4kcitations28works0.02yr avg
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Research Topics

Cellular Mechanics and Interactions(5), RNA Research and Splicing(4), Molecular Biology Techniques and Applications(4), Glioma Diagnosis and Treatment(3), Cell death mechanisms and regulation(3)

Publications28 total

Phase I study of the novel Cdc2/CDK1 and AKT inhibitor terameprocol in patients with advanced leukemias
Investigational New Drugs·2014· 49 cited
Mol Fingerprint Thy Ca Cell Lines suppl data JCEM 95 5338 2010
2013
Detailed Molecular Fingerprinting of Four New Anaplastic Thyroid Carcinoma Cell Lines and Their Use for Verification of RhoB as a Molecular Therapeutic Target
The Journal of Clinical Endocrinology & Metabolism·2010· 72 citedOpen Access
RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma
Molecular Cancer·2010· 33 citedOpen Access
A High-Content RNAi-Screening Assay to Identify Modulators of Cholesterol Accumulation in Niemann–Pick Type C Cells
Assay and Drug Development Technologies·2010· 13 cited
Chemogenomic Analysis Identifies Macbecin II as a Compound Specific for SMAD4‐Negative Colon Cancer Cells
Chemical Biology & Drug Design·2010· 4 citedOpen Access
High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation
BMC Genomics·2010· 77 citedOpen Access
P2‐141: Unraveling the process of tau hyperphosphorylation one gene at a time
Alzheimer s & Dementia·2008
Glioma cells on the run – the migratory transcriptome of 10 human glioma cell lines
BMC Genomics·2008· 63 citedOpen Access
Genome-wide RNAi synthetic lethality profiling to identify genetic determinants of Enzastaurin response
Clinical Cancer Research·2007
Quantitative and Qualitative Cellular Genomics: High Content Analysis as an End Point for HT‐RNAi Phenotype Profiling Using GE's IN Cell Platform
2007
Mitogen Activated Protein Kinase Kinase 3 is up-regulated in cancer, drives the invasive phenotype, and predicts short survival.
Cancer Research·2007
MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival
Molecular Cancer Therapeutics·2007· 114 citedOpen Access
Automated Characterization of cellular migration phenomena
2006
MAP-ing glioma invasion: MKK3 and p38 are drivers of glioma invasion and predict patient survival
Cancer Research·2006· 1 cited
Inhibition of Rho-Kinase Affects Astrocytoma Morphology, Motility, and Invasion through Activation of Rac1
Cancer Research·2005· 170 cited
The role of Autotaxin in glioblastoma multiforme invasion.
Cancer Research·2005
MAP2K3 and p38 are drivers of in vitro glioma invasion.
Cancer Research·2005
Radial Monolayer Cell Migration Assay
Humana Press eBooks·2003· 18 cited
Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
Journal of Cell Science·2003· 151 cited
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Frequent Co-authors

Michael E. Berens(16), Dominique B. Hoelzinger(10), David O. Azorsa(9), Wendy S. McDonough(8), Tim Demuth(8), Mitsutoshi Nakada(6), Luigi Mariani(5), Stephen W. Coons(5), Linsey B. Reavie(5), Jessica L. Rennert(5), Spyro Mousses(5), Alf Giese(4), David R. Holz(4), Satoko Nakada(4), Kristen Bisanz(4), Kristen R. Ross(3), Anna Joy(3), Nhan L. Tran(3), Elżbieta Kaczmarek(3), Rolf W. Seiler(3)